Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Acellular pertussis vaccine].

G Wiedermann1, F Ambrosch, H Vanura

  • 1Institut für Spezifische Prophylaxe und Tropenmedizin, Universität Wien.

Wiener Medizinische Wochenschrift (1946)
|January 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Diarrhea in tropical countries--what is to be done?].

MMW Fortschritte der Medizin·2004
Same author

Rapid antibody response after vaccination with a virosomal hepatitis a vaccine.

Infection·2004
Same author

[Use of pre-mixed insulins in diabetes treatment of young patients].

Endokrynologia, diabetologia i choroby przemiany materii wieku rozwojowego : organ Polskiego Towarzystwa Endokrynologow Dzieciecych·2003
Same author

In vivo-in vitro model for the assessment of clinically relevant antimalarial cross-resistance.

The American journal of tropical medicine and hygiene·2002
Same author

Molecular and immunological characterization of arginine kinase from the Indianmeal moth, Plodia interpunctella, a novel cross-reactive invertebrate pan-allergen.

Journal of immunology (Baltimore, Md. : 1950)·2001
Same author

Antimalarial activity of azithromycin, artemisinin and dihydroartemisinin in fresh isolates of Plasmodium falciparum in Thailand.

Acta tropica·2001
Same journal

Necrotizing fasciitis of the thigh-a devastating sign of intestinal perforation.

Wiener medizinische Wochenschrift (1946)·2026
Same journal

Regenerative therapies in rehabilitation with interfaces with occupational medicine, geriatrics, and oncology: the example of extracorporeal shock wave therapy.

Wiener medizinische Wochenschrift (1946)·2026
Same journal

Cerebral toxoplasmosis in patients with peripheral B-cell lymphoma : A case series and a literature review.

Wiener medizinische Wochenschrift (1946)·2026
Same journal

Post-pandemic rebound of rotavirus and adenovirus in pediatric gastroenteritis: a 6-year antigen-based surveillance study from Turkey.

Wiener medizinische Wochenschrift (1946)·2026
Same journal

Neuroaxis involvement in Chikungunya virus infection: a retrospective case series.

Wiener medizinische Wochenschrift (1946)·2026
Same journal

A complicated case of a spinal Scedosporium apiospermum infection with a favorable outcome-case report.

Wiener medizinische Wochenschrift (1946)·2026
See all related articles

Acellular pertussis vaccines, containing specific Bordetella pertussis antigens, offer improved tolerability over whole-cell vaccines. Preliminary studies of a new acellular vaccine show good tolerability and antibody responses.

Area of Science:

  • Immunology
  • Vaccinology
  • Microbiology

Background:

  • Acellular pertussis vaccines, utilizing components like pertussis toxin (PT) and filamentous hemagglutinin (FH), have been used in Japan since 1981.
  • Phase II studies indicate acellular vaccines offer better tolerability than whole-cell vaccines with comparable antibody responses.

Purpose of the Study:

  • To evaluate the tolerability and efficacy of a newly developed acellular pertussis vaccine.

Main Methods:

  • The study involved a newly developed acellular vaccine, approved by the Austrian Drug Commission.
  • Preliminary results from an ongoing study were analyzed.

Main Results:

  • The newly developed acellular vaccine demonstrated good tolerability in preliminary study results.

Related Experiment Videos

  • Antibody responses were of at least equal magnitude compared to existing vaccines.

    • Conclusions:

    • Acellular pertussis vaccines present a viable alternative to whole-cell vaccines due to improved tolerability.
    • Further studies are warranted to confirm efficacy and long-term protection rates.