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[Immunoglobulins in prevention and therapy]

W H Hitzig1

  • 1Universitäts-Kinderklinik Zürich, Schweiz.

Injected immunoglobulins (= Ig) substitute for a patient's failing active antibody production = passive immunization. They provide immediate protection (time factor!). Commercially available human Ig-concentrates contain mainly IgG. Poly- and mono-specific preparations are available. Five indications are listed. Only the first, prophylactic use, is treated extensively, because it must be familiar to every physician. Correct application enables to avoid many viral diseases (e.g. measles), toxin-mediated diseases (e.g. tetanus), and erythroblastosis fetalis.

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