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[Immunoglobulins in prevention and therapy]
1Universitäts-Kinderklinik Zürich, Schweiz.
Wiener Medizinische Wochenschrift (1946)
|January 1, 1991
Summary
Passive immunization with injected immunoglobulins (Ig) offers immediate protection by substituting for a patient's antibody production. Proper application of these IgG concentrates can prevent viral, toxin-mediated, and other serious diseases.
Area of Science:
- Immunology
- Pharmacology
Context:
- Injected immunoglobulins (Ig) provide passive immunization, supplementing failing active antibody production.
- Commercially available human Ig concentrates primarily contain IgG, with poly- and mono-specific preparations available.
Purpose:
- To elucidate the role and indications of injected immunoglobulins in clinical practice.
- To emphasize the importance of prophylactic immunoglobulin use for preventing various diseases.
Summary:
- Passive immunization via Ig infusion offers immediate protection, crucial for time-sensitive interventions.
- Key indications include prophylaxis against viral infections (e.g., measles), toxin-mediated diseases (e.g., tetanus), and erythroblastosis fetalis.
Impact:
- Highlights the critical role of physicians in understanding and applying immunoglobulin therapy.
- Correct application of immunoglobulins can significantly reduce the incidence of preventable infectious and immune-related conditions.