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Related Concept Videos

Computed Tomography01:10

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
X-ray Imaging01:24

X-ray Imaging

German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with X-rays, and by 1900, X-ray was widely...
X-ray Crystallography02:18

X-ray Crystallography

The size of the unit cell and the arrangement of atoms in a crystal may be determined from measurements of the diffraction of X-rays by the crystal, termed X-ray crystallography.
Diffraction
Diffraction is the change in the direction of travel experienced by an electromagnetic wave when it encounters a physical barrier whose dimensions are comparable to those of the wavelength of the light. X-rays are electromagnetic radiation with wavelengths about as long as the distance between neighboring...
Phase Contrast and Differential Interference Contrast Microscopy01:26

Phase Contrast and Differential Interference Contrast Microscopy

Phase-Contrast Microscopes
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
Electron Microscope Tomography and Single-particle Reconstruction01:07

Electron Microscope Tomography and Single-particle Reconstruction

Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...

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Related Experiment Video

Updated: Jun 22, 2026

Shaping the Amplitude and Phase of Laser Beams by Using a Phase-only Spatial Light Modulator
08:39

Shaping the Amplitude and Phase of Laser Beams by Using a Phase-only Spatial Light Modulator

Published on: January 28, 2019

X-Ray cone-beam phase tomography formulas based on phase-attenuation duality.

Xizeng Wu, Hong Liu

    Optics Express
    |June 6, 2009
    PubMed
    Summary

    This study introduces a novel phase-retrieval formula using phase-attenuation duality, enabling single-image 3D phase tomography for soft tissues. The method accounts for x-ray source coherence and detector resolution.

    Area of Science:

    • Medical Imaging
    • X-ray Optics
    • Computational Imaging

    Background:

    • Phase-retrieval techniques are crucial for quantitative X-ray imaging.
    • Existing methods often require multiple projections, limiting applications.
    • Incorporating source coherence and detector resolution improves image fidelity.

    Purpose of the Study:

    • To derive and validate a novel phase-retrieval formula based on phase-attenuation duality.
    • To develop a single-image 3D phase tomography method.
    • To extend the method for both small and large objects using established reconstruction algorithms.

    Main Methods:

    • Detailed derivation of the phase-retrieval formula incorporating phase-attenuation duality.
    • Inclusion of X-ray source coherence and detector resolution effects.

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    Last Updated: Jun 22, 2026

    Shaping the Amplitude and Phase of Laser Beams by Using a Phase-only Spatial Light Modulator
    08:39

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    Published on: January 28, 2019

    X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging
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    X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging

    Published on: September 11, 2011

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  • Combination with the Feldkamp-Davis-Kress (FDK) algorithm for 3D reconstruction.
  • Adaptation for helical phase tomography using Katsevich's formula for larger objects.
  • Main Results:

    • A robust phase-retrieval formula is presented, requiring only a single image.
    • The formula successfully integrates X-ray source coherence and detector resolution.
    • A 3D phase tomography formula is established for small soft tissue objects.
    • The approach is adaptable for helical tomography of larger objects.

    Conclusions:

    • The proposed phase-retrieval method offers significant advantages for phase tomography implementation.
    • Single-image acquisition simplifies the process and broadens applicability.
    • The developed formulas provide a powerful tool for quantitative 3D imaging of soft tissues.