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Related Concept Videos

The Replisome03:01

The Replisome

DNA replication is carried out by a large complex of proteins that act in a coordinated matter to achieve high-fidelity DNA replication. Together this complex is known as the DNA replication machinery or the replisome.
The synthesis of the leading and lagging strands is a highly coordinated process. To explain this, the “Trombone model” was proposed by Bruce Alberts in 1980. The DNA loop formation starts when a primer is synthesized on the parent lagging strand. The loop grows with the...
Replication in Prokaryotes02:35

Replication in Prokaryotes

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Related Experiment Video

Updated: Jun 22, 2026

Fabrication, Densification, and Replica Molding of 3D Carbon Nanotube Microstructures
09:23

Fabrication, Densification, and Replica Molding of 3D Carbon Nanotube Microstructures

Published on: July 2, 2012

Fabrication of a high-resolution periodical structure using a replication process.

Wei-Ching Chuang, Chi-Ting Ho, Wei-Chih Wang

    Optics Express
    |June 6, 2009
    PubMed
    Summary

    This study presents a fast method for creating submicrometer periodic structures using holographic interferometry and micro-molding. The technique accurately replicates grating patterns, offering a new way to prototype microstructures.

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    Fabrication, Densification, and Replica Molding of 3D Carbon Nanotube Microstructures
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    Fabrication of 1-D Photonic Crystal Cavity on a Nanofiber Using Femtosecond Laser-induced Ablation
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    Fabrication of 1-D Photonic Crystal Cavity on a Nanofiber Using Femtosecond Laser-induced Ablation

    Published on: February 25, 2017

    Area of Science:

    • Materials Science
    • Nanotechnology
    • Optics

    Background:

    • Periodic structures are crucial in optics and nanotechnology.
    • Existing fabrication methods can be slow and costly.
    • Rapid prototyping of submicrometer structures is in high demand.

    Purpose of the Study:

    • To develop a rapid and convenient procedure for prototyping submicrometer periodic structures.
    • To utilize holographic interferometry and micro-molding for precise pattern transfer.
    • To evaluate the accuracy of the developed fabrication technique.

    Main Methods:

    • Fabrication of a master periodic structure using holographic interference with a He-Cd laser.
    • Creation of a polydimethylsiloxane (PDMS) mold from the master structure.
    • Transfer of the grating pattern onto UV-curable epoxy using the PDMS mold.

    Main Results:

    • Successful prototyping of submicrometer periodic structures.
    • Accurate control over the grating's period and depth was achieved.
    • The epoxy grating showed <2% average error in period and 15% average error in depth reproduction.

    Conclusions:

    • The combined holographic interferometry and micro-molding technique offers an efficient method for submicrometer periodic structure fabrication.
    • This approach provides accurate replication of grating features.
    • The technique is suitable for rapid prototyping applications in micro- and nanofabrication.