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Updated: Jun 22, 2026
Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging
Published on: December 15, 2014
Comparison of diffusion-weighted images using short inversion time inversion recovery or chemical shift selective
Toshiki Kazama1, Katsuhiro Nasu, Yoshifumi Kuroki
1Department of Radiology, National Cancer Center Hospital East, Kashiwa, Japan. kazamat@fg7.so-net.ne.jp
Purpose:
Fat suppression is essential for diffusion-weighted imaging (DWI) in the body. However, the chemical shift selective (CHESS) pulse often fails to suppress fat signals in the breast. The purpose of this study was to compare DWI using CHESS and DWI using short inversion time inversion recovery (STIR) in terms of fat suppression and the apparent diffusion coefficient (ADC) value.
Materials And Methods:
DWI using STIR, DWI using CHESS, and contrast-enhanced T1-weighted images were obtained in 32 patients with breast carcinoma. Uniformity of fat suppression, ADC, signal intensity, and visualization of the breast tumors were evaluated.
Results:
In 44% (14/32) of patients there was insufficient fat suppression in the breasts on DWI using CHESS, whereas 0% was observed on DWI using STIR (P < 0.0001). The ADCs obtained for DWI using STIR were 4.3% lower than those obtained for DWI using CHESS (P < 0.02); there was a strong correlation of the ADC measurement (r = 0.93, P < 0.001).
Conclusion:
DWI using STIR may be excellent for fat suppression; and the ADC obtained in this sequence was well correlated with that obtained with DWI using CHESS. DWI using STIR may be useful when the fat suppression technique in DWI using CHESS does not work well.
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