Related Experiment Video
Updated: Jun 22, 2026

Endoscopic Vacuum Therapy for the Treatment of Anastomotic Leakage after Total Gastrectomy with Esophagojejunostomy
Published on: August 22, 2025
Half-solidification of nutrient does not decrease gastro-esophageal reflux events in patients fed via percutaneous
Kyoichi Adachi1, Kenji Furuta, Terumi Morita
1Department of Clinical Nursing, Shimane University Faculty of Medicine, 89-1 Enya-cho, Izumo-shi, Shimane 693-8501, Japan. kadachi@med.shimane-u.ac.jp
Half-solidifying nutrition for percutaneous endoscopic gastrostomy (PEG) tube feeding did not reduce gastro-esophageal reflux (GER) events. Acid reflux events even tended to increase with half-solid nutrient feeding in elderly patients.
Area of Science:
- Gastroenterology
- Clinical Nutrition
- Medical Devices
Background:
- Percutaneous endoscopic gastrostomy (PEG) feeding is crucial for patients with swallowing difficulties.
- Reflux-induced aspiration pneumonitis is a significant risk in PEG-fed patients.
- Gastro-esophageal reflux (GER) management is vital for patient safety.
Purpose of the Study:
- To evaluate the impact of half-solidifying nutrient formula on GER in PEG-fed patients.
- To compare acidic and non-acidic GER events between half-solid and liquid nutrient feeding.
- To assess the efficacy of modified nutrient consistency in preventing GER.
Main Methods:
- Esophageal multichannel intraluminal impedance and pH (MII-pH) monitoring was employed.
- 14 elderly patients receiving PEG feeding participated in the study.
- GER events were quantified during 4 hours post-feeding with both half-solid and liquid nutrients.
Main Results:
- No significant difference in total GER events was observed between half-solid and liquid feeding.
- A trend towards a higher number of acid reflux events was noted with half-solid feeding.
- The study found no benefit of half-solidification in reducing overall GER.
Conclusions:
- Half-solidification of nutrients is not effective in preventing GER in PEG feeding.
- Current feeding strategies may require re-evaluation for GER prevention.
- Further research into optimal nutrient formulations for PEG feeding is warranted.
Related Concept Videos
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube through...
Enteral Nutrition I: Orogastric and Nasogastric Feeding
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
Gastroesophageal Reflux Disease II: Clinical Features and Management
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
Gastroesophageal Reflux Disease
Gastroesophageal Reflux Disease I: Meaning and Pathophysiology
Peptic Ulcer Disease V: Surgical Management and Nursing Care
Surgical Interventions for Peptic Ulcer Disease