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Related Experiment Video

Updated: Jun 22, 2026

Using Eye-tracking to Assess the Relative Importance of Visual and Vestibular Input to Subcortical Motion Processing in the Roll Plane
07:24

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Published on: August 22, 2025

Extending the eXpanded Nystagmus Acuity Function for vertical and multiplanar data.

J B Jacobs1, L F Dell'osso

  • 1Daroff-Dell'Osso Ocular Motility Laboratory, Louis Stokes Cleveland Department of Veterans Affairs Medical Center and CASE Medical School, Cleveland, OH 44106, USA. jx24@case.edu

Vision Research
|June 9, 2009
PubMed
Summary
This summary is machine-generated.

The updated eXpanded Nystagmus Acuity Function (NAFX) improves predictions of visual acuity in nystagmus patients. This enhanced NAFX provides more accurate, objective measures for diverse eye movements and all age groups.

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Area of Science:

  • Ophthalmology
  • Neuroscience
  • Biomedical Engineering

Background:

  • The original Nystagmus Acuity Function (NAFX) provided a measure of visual acuity based on foveation times.
  • Irregularities in the original NAFX tau-surface limited its clinical predictive value due to subject data idiosyncrasies.
  • Existing NAFX models were primarily designed for uniplanar eye movement data.

Purpose of the Study:

  • To update and extend the functionality of the NAFX for broader clinical application and improved predictive accuracy.
  • To develop a more robust mathematical model for NAFX calculations, addressing previous data-related irregularities.
  • To incorporate multiplanar eye movement data and age-related visual acuity relationships into the NAFX.

Main Methods:

  • Replaced the original NAFX tau-surface with an idealized mathematical function to correct for data irregularities.
  • Combined horizontal and vertical eye movement data using vector summation to analyze multiplanar waveforms.
  • Integrated age-related visual acuity data to enhance the correlation between NAFX values and patient acuity.

Main Results:

  • The updated NAFX demonstrated equivalent results to the original for uniplanar data.
  • Biplanar data analysis yielded results comparable to uniplanar data of similar magnitude.
  • The enhanced NAFX showed improved accuracy in predicting visual acuity across diverse patient populations and eye movement types.

Conclusions:

  • The updated NAFX offers greater accuracy in predicting visual acuity for individuals with uniplanar and multiplanar nystagmus.
  • This extended NAFX provides an improved objective measure for assessing post-therapy waveform improvements.
  • The enhanced NAFX facilitates better therapeutic strategy selection for a wider spectrum of nystagmus patients.