Health issues of the late preterm infant

Ashwin Ramachandrappa1, Lucky Jain

  • 1Department of Pediatrics, Division of Neonatology, Emory University School of Medicine, Atlanta, GA 30322, USA. ashwin_ramachandrappa@oz.ped.emory.edu

Insights

Late preterm infants, once considered low-risk, face higher mortality and increased complications. These infants require significant healthcare resources and may experience long-term neurodevelopmental issues.

Area of Science:

  • Neonatology
  • Perinatology
  • Pediatric Medicine

Background:

  • Late preterm infants (34-36 weeks gestation) were historically considered low-risk due to successful early treatments.
  • Recent evidence indicates these infants are not as benign as previously assumed.
  • They represent a significant proportion of preterm births and resource utilization.

Purpose of the Study:

  • To highlight the increased risks and complications associated with late preterm birth.
  • To underscore the need for renewed attention to this vulnerable population.
  • To discuss potential long-term neurodevelopmental consequences.

Main Methods:

  • Review of current evidence and emerging data on late preterm infants.
  • Comparative analysis of outcomes between late preterm and term infants.
  • Identification of common neonatal complications and resource utilization patterns.

Main Results:

  • Late preterm infants exhibit increased mortality compared to term infants.
  • Higher incidence of complications such as transient tachypnea of newborn (TTN), respiratory distress syndrome (RDS), and jaundice.
  • Increased likelihood of prolonged neonatal intensive care unit (NICU) stays and feeding difficulties.

Conclusions:

  • Late preterm infants represent a high-risk group requiring closer monitoring and management.
  • These infants incur significant healthcare costs and resource demands.
  • Potential long-term neurodevelopmental deficits warrant further investigation and follow-up.

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