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Related Experiment Video

Updated: Jun 22, 2026

Multiplexed Fluorescent Immunohistochemical Staining of Four Endometrial Immune Cell Types in Recurrent Miscarriage
05:16

Multiplexed Fluorescent Immunohistochemical Staining of Four Endometrial Immune Cell Types in Recurrent Miscarriage

Published on: August 4, 2021

Diagnosing miscarriage.

Cecilia Bottomley1, Tom Bourne

  • 1St George's University of London, Cranmer Terrace, London, UK. ceciliabottomley@doctors.org.uk

Best Practice & Research. Clinical Obstetrics & Gynaecology
|June 9, 2009
PubMed
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Miscarriage is a common pregnancy complication. Accurate diagnosis using transvaginal ultrasound and clinical history is crucial for patient management and predicting outcomes, minimizing psychological effects.

Area of Science:

  • Reproductive Medicine
  • Obstetrics & Gynecology
  • Medical Imaging

Background:

  • Miscarriage is the most frequent serious pregnancy complication, impacting 11-20% of recognized pregnancies.
  • Accurate diagnosis is essential for appropriate management and patient counseling.
  • Psychological effects following miscarriage can be significant and prolonged.

Purpose of the Study:

  • To review diagnostic criteria for miscarriage.
  • To evaluate the role of ultrasound in miscarriage diagnosis.
  • To highlight the importance of accurate diagnosis for predicting outcomes and managing psychological impact.

Main Methods:

  • Review of evidence-based criteria for miscarriage diagnosis.
  • Assessment of transvaginal ultrasound (TVS) in diagnosing miscarriage.

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Platform for Quantitative Detection of Endometrial Immune Cells Based on Immunohistochemistry and Digital Image Analysis
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Platform for Quantitative Detection of Endometrial Immune Cells Based on Immunohistochemistry and Digital Image Analysis

Published on: October 13, 2023

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Is My Mouse Pregnant? High-Frequency Ultrasound Assessment

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Related Experiment Videos

Last Updated: Jun 22, 2026

Multiplexed Fluorescent Immunohistochemical Staining of Four Endometrial Immune Cell Types in Recurrent Miscarriage
05:16

Multiplexed Fluorescent Immunohistochemical Staining of Four Endometrial Immune Cell Types in Recurrent Miscarriage

Published on: August 4, 2021

Platform for Quantitative Detection of Endometrial Immune Cells Based on Immunohistochemistry and Digital Image Analysis
07:46

Platform for Quantitative Detection of Endometrial Immune Cells Based on Immunohistochemistry and Digital Image Analysis

Published on: October 13, 2023

Is My Mouse Pregnant? High-Frequency Ultrasound Assessment
02:39

Is My Mouse Pregnant? High-Frequency Ultrasound Assessment

Published on: March 18, 2021

  • Analysis of maternal history and ultrasound features for diagnostic prediction.

    • Main Results:

    • Transvaginal ultrasound (TVS) is the primary diagnostic tool for miscarriage.
    • Complete miscarriage diagnosis requires serial biochemical confirmation if an intrauterine gestation sac was not previously visualized.
    • Retained tissue is found in 45% of cases after clinical complete miscarriage; ectopic pregnancy occurs in 6% of cases with an empty uterus and miscarriage history.

    Conclusions:

    • Adherence to evidence-based criteria for miscarriage diagnosis is vital.
    • Maternal history and ultrasound features aid in predicting pregnancy outcomes.
    • Accurate diagnosis and management are essential to mitigate the significant psychological effects of miscarriage.