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Murine Model of Epicutaneously-Induced Immunomodulation
Published on: June 24, 2025
Diverse immune responses to orally administered heat-killed cell preparation of Enterococcus faecalis strain EC-12 in
Tohru Yoshikawa1, Ryo Inoue, Yoko Yoshida
1Laboratory of Animal Science, Kyoto Prefectural University, Shimogamo, Kyoto, Japan.
Bioscience, Biotechnology, and Biochemistry
|June 9, 2009
Abstract:
Diverse immune responses to an orally administered heat-killed cell preparation of Enterococcus faecalis strain EC-12 (EC-12) among jejunal-Peyer's patches (PPs), ileal-PPs, mesenteric lymph nodes (MLNs), and spleen were compared by real-time PCR in mice. Intriguingly, distinct responses to EC-12 were observed in the various tissues. This study indicates a site-specific response to orally administered bacteria, particularly in jejunal- and ileal-PPs.
