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[Hyperviscosity. An independent risk factor after a survived stroke].
1Klinik für Physikalische Medizin und Rehabilitation, AKH, Wien, Osterreich.
Acta Medica Austriaca
|January 1, 1991
Summary
High blood viscosity is a significant risk factor for poor prognosis in patients after a first stroke. This finding is independent of other known cardiovascular risk factors, highlighting the importance of blood flow properties.
Area of Science:
- Cardiovascular Medicine
- Rheology
- Neurology
Context:
- Pathologic blood flow properties are linked to worse outcomes in arteriosclerotic diseases, particularly post-stroke.
- A prospective study investigated rheologic parameters in patients with a recent first stroke.
Purpose:
- To test the hypothesis that abnormal blood flow properties (blood viscosity) predict poorer prognosis in patients following a first stroke.
Summary:
- 625 patients with a recent first stroke were assessed for blood viscosity and other determinants. Over two years, 71 patients reached an endpoint (second stroke, heart attack, or cardiovascular death). Native blood viscosity was significantly higher in patients with an endpoint compared to those without.
- Key determinants of blood viscosity including hematocrit, plasma viscosity, fibrinogen, erythrocyte sedimentation rate, leukocytes, cholesterol, triglycerides, blood pressure, BMI, and smoking status were analyzed.
Impact:
- High native blood viscosity is identified as an independent risk factor for adverse cardiovascular events in patients who have experienced a first stroke.
- This research underscores the clinical significance of rheologic measurements in stroke patient management and risk stratification.