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Related Experiment Video

Updated: Jun 22, 2026

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis
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MR-lymphangiography at 3.0 T--a feasibility study.

Mike Notohamiprodjo1, Ruediger G H Baumeister, Tobias F Jakobs

  • 1Department of Clinical Radiology, University-Hospitals Munich, Campus Grosshadern, Marchioninistrasse 15, 81377 Munich, Germany. mike.notohamiprodjo@med.uni-muenchen.de

European Radiology
|June 9, 2009
PubMed
Summary

Contrast-enhanced MR-lymphangiography (MRL) at 3.0 T effectively visualizes peripheral lymphatic system abnormalities. This technique offers high spatial resolution, aiding in diagnosing conditions like lymphedema and planning microsurgical treatments.

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Area of Science:

  • Radiology
  • Medical Imaging
  • Lymphatic System Imaging

Background:

  • Peripheral lymphatic system abnormalities can be challenging to diagnose.
  • Accurate visualization is crucial for treatment planning and monitoring.

Purpose of the Study:

  • To establish and evaluate contrast-enhanced MR-lymphangiography (MRL) at 3.0 Tesla (T).
  • To assess MRL's efficacy in detecting and visualizing peripheral lymphatic system abnormalities.

Main Methods:

  • Sixteen patients underwent MRL at 3.0 T using a high-resolution isotropic T1w-3D-GRE-(FLASH) sequence.
  • Intracutaneous injection of gadolinium-diethylene-triamine-pentaacetic-acid was administered.
  • Image quality, lymph vessel depiction, venous contamination, and lymphatic drainage were evaluated.

Main Results:

  • MRL at 3.0 T provided good to excellent overall image quality and lymph vessel depiction in most cases.
  • Diagnostic imaging was achieved in 15/16 patients, with minor issues in one case due to subcutaneous contrast injection.
  • Delayed lymphatic drainage was observed in lymphedematous extremities, correlating with ectatic vessels and diffuse contrast medium drainage.

Conclusions:

  • Contrast-enhanced MRL at 3.0 T offers high spatial resolution and detailed anatomical visualization of peripheral lymph vessels.
  • MRL is a valuable tool for diagnosing lymphatic abnormalities and planning microsurgical interventions.
  • The technique demonstrates potential for monitoring treatment efficacy in lymphatic disorders.