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Updated: Jun 22, 2026

Gastric Mucosa Quantitative Polymerase Chain Reaction Analysis for Detecting Helicobacter pylori and Antibiotic Resistance
Published on: March 7, 2025
Parotid mucosa-associated lymphoid tissue lymphoma regression after Helicobacter pylori eradication
Hiroshi Iwai1, Naoto Nakamichi, Kaori Nakae
1Department of Otolaryngology, Takii Hospital, Kansai Medical University, Osaka, Japan. iwai@takii.kmu.ac.jp
Abstract:
A 60-year-old woman with Sjögren's syndrome showed recurrence of parotid mucosa-associated lymphoid tissue (MALT) lymphoma with a simultaneous increase of serum sIL-2R antigen levels 10 years after surgical treatment. Helicobacter pylori infection had been detected in the stomach since the beginning of the lymphoma. Although H. pylori was not detected in the recurrent parotid lymphoma, antibiotic therapy contributed not only to successful eradication of gastric H. pylori but also to disappearance of the recurrent lymphoma. Further studies on the mechanisms of occurrence of extragastric MALT lymphomas are needed to establish the treatment of extragastric MALT lymphomas.
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