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Updated: Jun 22, 2026
Murine Echocardiography of Left Atrium, Aorta, and Pulmonary Artery
Published on: February 20, 2017
An alternative echocardiographic method to estimate mean pulmonary artery pressure: diagnostic and clinical
Javier F Aduen1, Ramon Castello, Marcelo M Lozano
1Division of Pulmonary Medicine, Mayo Clinic, Jacksonville, Florida, USA.
Background:
The aim of this study was to evaluated an alternative echocardiographic method to calculate mean pulmonary arterial pressure (MPAP).
Methods:
One hundred two patients were studied with simultaneous right-heart catheterization (RHC) and echocardiography. MPAP was calculated by adding the right ventricular-right atrial mean systolic gradient to right atrial pressure.
Results:
The mean difference between MPAP calculated using this method and RHC-derived MPAP was -1.6 mm Hg, less than that of traditional systolic pulmonary arterial pressure (SPAP; -6.4 mm Hg) and MPAP estimated using the pulmonary regurgitation method (-13.9 mm Hg). The median absolute percentage difference of the MPAP calculations relative to RHC was significantly less with this method than with the pulmonary regurgitation method (18% vs 71%; P < .001) and similar to the SPAP method (both 18%; P = .30).
Conclusion:
MPAP calculated using the proposed method is as accurate as SPAP calculation and less variable than previous methods, thus allowing widespread clinical use.
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