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Related Experiment Video

Updated: Jun 22, 2026

Left Atrial Ligation in the Avian Embryo as a Model for Altered Hemodynamic Loading During Early Vascular Development

Left Atrial Ligation in the Avian Embryo as a Model for Altered Hemodynamic Loading During Early Vascular Development

Published on: June 16, 2023

Hemipalatal hypoplasia.

Ying-Chien Tan¹, Philip Kuo-Ting Chen

¹Department of Plastic, Reconstructive and Aesthetic Surgery, KK Women's & Children's Hospital, Singapore.

The Journal of Craniofacial Surgery

|June 10, 2009

Summary

This summary is machine-generated.

Idiopathic hemipalatal hypoplasia can cause asymmetric velopharyngeal incompetence (VPI). Centralized pharyngeal flaps appear more effective for surgical correction of associated speech problems than skewed flaps.

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Last Updated: Jun 22, 2026

Left Atrial Ligation in the Avian Embryo as a Model for Altered Hemodynamic Loading During Early Vascular Development

Left Atrial Ligation in the Avian Embryo as a Model for Altered Hemodynamic Loading During Early Vascular Development

Published on: June 16, 2023

Area of Science:

Plastic Surgery
Speech Pathology
Otolaryngology

Background:

Asymmetric velopharyngeal incompetence (VPI) typically stems from conditions like cleft palate or hemifacial microsomia (HFM).
Cases of asymmetric VPI without these underlying causes are rare, often linked to unilateral velopharyngeal hypoplasia.

Observation:

This study reviewed 5 patients with asymmetric VPI due to idiopathic hemipalatal hypoplasia, excluding clefts, HFM, or significant facial asymmetry.
Presentations included nasal regurgitation (4/5), tonsillar enlargement (2/5), and an ipsilateral tongue mass (1/5).

Findings:

Two patients improved with speech therapy; three required surgery for speech issues.
Initial surgery with a skewed pharyngeal flap was less effective than subsequent centralized pharyngeal flaps for correcting speech problems.

Implications:

Idiopathic hemipalatal hypoplasia presents distinctively compared to other causes of asymmetric VPI.
Centralized pharyngeal flaps demonstrate greater reliability for surgical correction of speech disorders in these patients.