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Related Concept Videos

Cell Motility through Blebbing01:16

Cell Motility through Blebbing

Blebs are a type of membrane protrusion formed by the internal hydrostatic pressure of the cytoplasm. Blebs are observed in several cell types, including fibroblasts, immune cells, and single-celled organisms like the amoeba. The primary function of blebs is cell locomotion and apoptosis, but they are also found during necrosis and cell division. The life cycle of a bleb comprises an initiation phase followed by the expansion and retraction phases.
Blebbing Through the Matrix
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Microtubules in Cell Motility01:24

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Microtubules are thick hollow cylindrical proteins that help form the cytoskeleton. Microtubules have varied roles in the cell. These filaments help form cellular appendages like cilia and flagella, which are responsible for locomotion. The cilia arise from basal bodies, separated from the main body by a membrane-like structure forming the transition zone. This zone is the gate for the entry of lipids and proteins, creating a unique composition of lipids and proteins in the ciliary membrane and...
Microtubules in Cell Motility01:24

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The ciliary structures were first seen in 1647 by Antonie Leeuwenhoek while observing the protozoans. In lower organisms, these appendages are responsible for cell movement, while in higher organisms, these appendages help in the movement of the extracellular fluids within the body cavities.
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Related Experiment Video

Updated: Jun 22, 2026

Direct Force Measurements of Subcellular Mechanics in Confinement using Optical Tweezers
09:56

Direct Force Measurements of Subcellular Mechanics in Confinement using Optical Tweezers

Published on: August 31, 2021

Optical torques guiding cell motility.

Gabriel Biener1, Emannuel Vrotsos, Kiminogu Sugaya

  • 1CREOL, The College of Optics and Photonics, University of Central Florida, Orlando, FL 32816, USA.

Optics Express
|June 10, 2009
PubMed
Summary
This summary is machine-generated.

Polarized light can control cell movement by influencing actin filaments. This noninvasive method allows for active guidance of large cell groups, offering new insights into cell motility and environmental interactions.

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Last Updated: Jun 22, 2026

Direct Force Measurements of Subcellular Mechanics in Confinement using Optical Tweezers
09:56

Direct Force Measurements of Subcellular Mechanics in Confinement using Optical Tweezers

Published on: August 31, 2021

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Area of Science:

  • Biophysics
  • Cell Biology
  • Optical Physics

Background:

  • Cell motility is primarily driven by actin filament dynamics.
  • The influence of environmental factors on cell migration and differentiation requires further investigation.

Purpose of the Study:

  • To investigate the effect of polarized optical fields on the actin cytoskeleton.
  • To demonstrate the potential for noninvasive control of cell motility and group dynamics.

Main Methods:

  • Utilizing polarized optical fields to apply controllable torques on the actin network.
  • Employing systematic experiments and stochastic modeling to analyze cell behavior.

Main Results:

  • Demonstrated that polarized optical fields can influence the actin treadmilling process, a key factor in cell motility.
  • Showcased the ability to actively guide the dynamics of large cell populations noninvasively.

Conclusions:

  • Polarized optical fields offer a novel, noninvasive method to control cell motility.
  • This approach provides a new tool for understanding and manipulating cell migration and differentiation influenced by environmental factors.