Related Experiment Video
Updated: Jun 22, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Radiation dose from multidetector row CT imaging for acute stroke
Anisa Mnyusiwalla1, Richard I Aviv, Sean P Symons
1Department of Medical Imaging, Division of Neuroradiology, Sunnybrook Health Sciences Center, University of Toronto, Toronto, ON, Canada.
Insights
Comprehensive computed tomography (CT) imaging for acute stroke delivers a mean effective radiation dose of 16.4 mSv. This high dose necessitates dose reduction strategies and consideration of MRI as an alternative.
Area of Science:
- Radiology
- Medical Imaging
- Radiation Dosimetry
Background:
- Acute stroke management relies on advanced imaging techniques.
- Computed tomography (CT) plays a crucial role in diagnosing and characterizing stroke.
- Assessing radiation exposure from comprehensive CT protocols is vital for patient safety.
Purpose of the Study:
- To quantify the radiation dose delivered by a comprehensive CT imaging protocol for acute stroke.
- To evaluate the effective dose and dose-length product (DLP) for each component of the protocol.
Main Methods:
- Retrospective analysis of 95 CT examinations over 18 months using an acute stroke protocol.
- Protocol included unenhanced head CT, CT angiography (CTA), and CT perfusion/permeability.
- Effective doses were calculated from dose-length products (DLP) using region-specific conversion factors.
Main Results:
- The mean effective dose for the comprehensive CT acute stroke protocol was 16.4 mSv.
- This dose is approximately six times higher than that of an unenhanced CT head scan (2.7 mSv).
- CT angiography (CTA) contributed the most to the effective dose (mean 5.4 mSv), followed by CT perfusion (mean 4.9 mSv).
Conclusions:
- Comprehensive CT protocols for acute stroke result in significant radiation exposure.
- The detailed anatomical and physiological data obtained must be weighed against radiation risks.
- Implementing aggressive dose reduction strategies and considering MRI as an alternative are recommended.
Introduction:
The objective of this study was to determine the radiation dose delivered during comprehensive computed tomography (CT) imaging for acute stroke.
Methods:
All CT examinations performed over 18 months using our acute stroke protocol were included. Protocol includes an unenhanced CT head, CT angiography from the arch to vertex, CT perfusion/permeability, and an enhanced CT head. All imaging was acquired with a 64-MDCT. Examinations where any element of the protocol was repeated or omitted due to mistimed injection or patient motion were excluded. Dose-length products (DLP) for all components of each examination were obtained from dose reports generated at the time of acquisition, separating neck, and head calculations. Effective doses for each examination were calculated using the DLP and normalized values of effective dose per DLP appropriate for the body regions imaged.
Results:
Ninety-five examinations were included. Mean DLP was 6,790.0 mGy x cm. Effective doses ranged from 11.8 to 27.3 mSv, mean effective dose of 16.4 mSv. Mean effective dose for acquisition of the unenhanced head was 2.7 mSv. Largest contribution to effective dose was the CTA with a mean effective dose of 5.4 mSv. Mean effective dose for the CT perfusion was 4.9 mSv.
Conclusion:
A comprehensive CT acute stroke protocol delivered a mean effective dose of 16.4 mSv, which is approximately six times the dose of an unenhanced CT head. These high-dose results must be balanced with the benefits of the detailed anatomic and physiologic data obtained. Centers should implement aggressive dose reduction strategies and freely use MR as a substitute.
Related Concept Videos
Radiological Investigation I: X-ray and CT
Imaging Studies for Cardiovascular System V: CT
Computed Tomography
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Imaging Studies III: Computed Tomography
Imaging Studies I: CT and MRI
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
