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IUDs and PID: a comparative trial of strings versus stringless devices.
D M Potts1, C B Champion, M Kozuh-Novak
1Family Health International, Research Triangle Park, NC 27709.
Advances in Contraception : the Official Journal of the Society for the Advancement of Contraception
|June 1, 1991
Summary
Intrauterine device (IUD) marker strings do not significantly increase the risk of pelvic inflammatory disease (PID). This clinical trial found no difference in PID rates between IUDs with or without strings.
Area of Science:
- Reproductive Health
- Infectious Diseases
- Medical Devices
Background:
- Pelvic inflammatory disease (PID) is a significant concern for intrauterine device (IUD) users.
- The potential role of IUD marker strings in PID etiology has been debated.
- Understanding risk factors for PID is crucial for patient safety and IUD efficacy.
Purpose of the Study:
- To investigate whether intrauterine device (IUD) marker strings contribute to the development of pelvic inflammatory disease (PID).
- To compare the incidence of PID in women using IUDs with and without marker strings.
Main Methods:
- An international, multicentered clinical trial involving 1265 women.
- Random allocation to receive either a standard TCu200 IUD with marker strings or a TCu200 IUD without marker strings.
- Follow-up for 12 months post-insertion, monitoring for PID and other infections.
Main Results:
- No statistically significant difference in the incidence of PID between the two IUD groups.
- Similar 12-month life table termination and overall continuation rates for both groups.
- Higher removal rates for bleeding/pain in the string group, but no difference in reported complaints.
Conclusions:
- Intrauterine device (IUD) marker strings do not appear to play a significant role in the etiology of PID.
- The presence or absence of IUD marker strings does not impact PID risk.
- IUD strings may be associated with increased removal for bleeding/pain but not infection.