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A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection
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[The placental structural organization in pulmonary tuberculosis]

L A Cherdantseva, A V Iakimova, A P Nadeev

    Arkhiv Patologii
    |June 11, 2009
    PubMed

    The placentas taken from 83 pregnant women with gestation of 37-40 weeks were morphologically and morphometrically studied. Group 1 comprised 23 pregnant women with pulmonary tuberculosis. Group 2 included 40 pregnant women whose pregnancy was complicated by gestosis. Group 3 (control) consisted of 20 healthy pregnant women. Group 1 was found to have chronic placental insufficiency caused by abnormal placental villous immaturity the basis of which was impaired processes of villous differentiation and terminal villous angiogenesis. In most cases, chronic placental insufficiency was compensatory in all the groups under study; but there were differences in compensatory mechanisms. The leading mechanism was cellular in Groups 1 and 2, the mixed (vascular and cellular) types of compensation was predominant in Group 3 (control).

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