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Regulation of Stroke Volume

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The regulation of stroke volume, which is the amount of blood the heart pumps out during each heartbeat, is critical for maintaining a healthy circulatory system. Stroke volume is influenced by three main factors: preload, contractility, and afterload.
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Cardiac output (CO), the amount of blood the heart pumps per minute, is a parameter in cardiovascular physiology determined by stroke volume and heart rate. Stroke volume, the amount of blood pushed from one of the ventricles per heartbeat, is influenced by preload, afterload, and contractility.
Preload
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Cardiac Output and Stroke Volume

Cardiac Output and Stroke Volume

Cardiac output (CO) is an integral aspect of human physiology, reflecting the heart's efficiency and responsiveness to the body's needs. It represents the volume of blood that the left or right ventricle ejects into the aorta or pulmonary trunk each minute. The CO is calculated by multiplying the heart rate (HR)—the number of heartbeats per minute—by the stroke volume (SV)—the amount of blood pumped out with each heartbeat.
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Related Experiment Video

Updated: Jun 22, 2026

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation

Published on: July 20, 2022

Left atrial volume as a predictor of heart function.

G Valocik¹, P Mitro, L Druzbacka

¹IIIrd Department of Internal Medicine, University Hospital, Louis Pasteur's Hospital, Faculty of Medicine, Safarikiensis University, Kosice, Slovakia. valocik@central.medic.upjs.sk

Bratislavske Lekarske Listy

|June 11, 2009

Summary

This study found that increased left atrial volume is strongly associated with left ventricular systolic and diastolic dysfunction. Left ventricular mass was the best predictor of enlarged left atrial volume.

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Last Updated: Jun 22, 2026

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation

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Published on: July 20, 2022

Biventricular Assessment of Cardiac Function and Pressure-Volume Loops by Closed-Chest Catheterization in Mice

Biventricular Assessment of Cardiac Function and Pressure-Volume Loops by Closed-Chest Catheterization in Mice

Published on: June 15, 2020

Area of Science:

Cardiology
Echocardiography
Cardiac Function

Background:

Left atrial volume is linked to cardiovascular risk factors.
Understanding the relationship between left atrial volume and left ventricular function is crucial for cardiovascular health assessment.

Purpose of the Study:

To investigate the association between left atrial volume and left ventricular systolic and diastolic functions.
To determine the predictive value of left ventricular mass on left atrial volume.

Main Methods:

Retrospective analysis of transthoracic echocardiographic data from 268 patients.
Correlation of key echocardiographic variables of systolic and diastolic function with indexed left atrial volume.

Main Results:

Left atrial volume significantly increased with deteriorating diastolic function (impaired relaxation, pseudonormalized, restrictive).
Significant differences in left atrial volume were observed between normal systolic function and systolic dysfunction.
Left ventricular mass was identified as the strongest predictor of enlarged left atrial volume.

Conclusions:

A strong association exists between left atrial volume and left ventricular systolic and diastolic dysfunction.
Left atrial volume serves as a significant indicator of impaired cardiac function.
Left ventricular mass is a key determinant of increased left atrial volume.