[Methods for studying eugenol]

A steady tendency toward the extensive use of phytogenous medicinal products well apparent in the recent years involves dental materials. Over one third of the dentistry products contain eugenol, the main component of the clove essential oil. This study is focused on the development of a method for the detection and quantitative measurement ofeugenol in a variety of stomatological products, includling filling materials, and other preparations. The samples for analysis were prepared taking into account physical and chemical properties of the substance of interest, such as high partial pressure over the liquid phase. We investigated the equilibrium vapour phase by capillary gas chromatography with the use of a mass-spectral detector. A method for the detection and quantitative assay of eugenol in dental materials and-filling agents was developed. Its sensitivity limit is 10 ng/ml for liquid samples and 25 mcg/g for solid ones. Metrologic characteristics of the method make it suitable for the detection of eugenol in dental fillings after their long-term contact with biological tissues.