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Overview of Systemic Arteries

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The human body is a complex, well-organized machine, and at the heart of its operations lies the circulatory system. This network of blood vessels, which includes systemic arteries, plays a vital role in maintaining life by transporting nutrients, oxygen, and waste products to and from cells throughout the body.
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Psychoneuroimmunology: Cardiovascular Disease

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Myocarditis I: Introduction

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Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

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The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...

Pericarditis I: Introduction

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Primary Sjogren's Syndrome Associated with Lung Adenocarcinoma: Probing the Potential Common Pathogenic Mechanisms and Experimental Verification

Primary Sjogren's Syndrome Associated with Lung Adenocarcinoma: Probing the Potential Common Pathogenic Mechanisms and Experimental Verification

Published on: September 20, 2024

Cardiovascular involvement in primary systemic vasculitis.

Chetan Mukhtyar¹, Paul Brogan, Raashid Luqmani

¹Rheumatology Department, University of Oxford, Oxford, UK.

Best Practice & Research. Clinical Rheumatology

|June 11, 2009

Summary

This summary is machine-generated.

Primary systemic vasculitis increases cardiovascular risks due to inflammation and treatments. This review examines effects on heart disease, heart failure, and hypertension, offering management recommendations.

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Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

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Area of Science:

Cardiovascular Medicine
Rheumatology
Immunology

Background:

Primary systemic vasculitides are autoimmune diseases causing blood vessel inflammation.
Modern treatments improve survival but may increase cardiovascular complications.
Chronic inflammation and therapies contribute to cardiovascular events.

Purpose of the Study:

To review the cardiovascular impact of primary systemic vasculitides.
To analyze effects on coronary artery disease, heart failure, hypertension, and aortic aneurysms.
To explore the interplay of autoimmune mechanisms, endothelium, and treatment on cardiovascular health.

Main Methods:

Systematic review of existing data.
Analysis of cardiovascular end points across all age groups.
Examination of etiological factors including endothelial activation and atherogenic potential.

Main Results:

Primary systemic vasculitis is associated with increased cardiovascular morbidity.
Endothelial dysfunction, autoimmune processes, and treatments are key contributors.
Specific risks include coronary artery disease, congestive cardiac failure, hypertension, and aortic aneurysms.

Conclusions:

Cardiovascular complications are a significant concern in primary systemic vasculitis.
Integrated management strategies are needed to address these risks.
Further research should focus on preventative and therapeutic interventions for cardiovascular health.