Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Sensitivity, Specificity, and Predicted Value01:13

Sensitivity, Specificity, and Predicted Value

In healthcare diagnostics, laboratory tests play a crucial role in identifying and diagnosing a wide range of medical conditions. However, interpreting test results is not always straightforward. An abnormal test result does not always confirm the presence of a disease, just as a normal result does not guarantee its absence. To assess the reliability of these diagnostic tools, healthcare practitioners rely on two key statistical indicators: sensitivity and specificity.
Sensitivity is the...
Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Beyond weight loss: predictors of treatment satisfaction and patient-reported outcomes in incretin-based therapies. A cross-sectional study.

Frontiers in endocrinology·2026
Same author

Effects of auricular vagal neuromodulation therapy combined with slow-paced diaphragmatic breathing in individuals with postural tachycardia syndrome: a randomised controlled trial protocol.

BMJ open·2026
Same author

Climate Matters-Association Between Ambient Temperature During Pregnancy and Birth Length in Austria Between 1984 and 2014-A Population-Based Study.

American journal of human biology : the official journal of the Human Biology Council·2026
Same author

Trends in visual impairment among Austrian conscripts (1965-2003) after screening introduction : A retrospective, descriptive study.

Wiener klinische Wochenschrift·2026
Same author

Linking health-related behaviors to quality of life in older adults: a latent class analysis.

Innovation in aging·2026
Same author

Suicide Rates Among Patients Receiving Palliative Care-Descriptive Results of a National Cohort Study.

Journal of clinical medicine·2026

Related Experiment Video

Updated: Jun 22, 2026

Signal Acquisition, Score Interpretation, and Economics of a Non-Invasive Point-of-Care Test for Coronary Artery Disease
06:16

Signal Acquisition, Score Interpretation, and Economics of a Non-Invasive Point-of-Care Test for Coronary Artery Disease

Published on: August 9, 2024

PSA testing in Austria: induced morbidity and saved mortality.

Christian Vutuc1, Thomas Waldhoer, Gerhard Lunglmayr

  • 1Department of Epidemiology, Centre of Public Health, Medical University of Vienna, Vienna, Austria.

European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)
|June 11, 2009
PubMed
Summary

Opportunistic prostate-specific antigen (PSA) screening in Austria identified 9,648 additional men with asymptomatic prostate cancer. To prevent one prostate cancer death in men aged 50-69, 18.8 asymptomatic cases were detected.

Related Experiment Videos

Last Updated: Jun 22, 2026

Signal Acquisition, Score Interpretation, and Economics of a Non-Invasive Point-of-Care Test for Coronary Artery Disease
06:16

Signal Acquisition, Score Interpretation, and Economics of a Non-Invasive Point-of-Care Test for Coronary Artery Disease

Published on: August 9, 2024

Area of Science:

  • Oncology
  • Public Health
  • Epidemiology

Background:

  • Opportunistic prostate-specific antigen (PSA) screening has significantly increased prostate cancer incidence in Austria.
  • The impact of PSA screening on prostate cancer incidence and mortality requires careful evaluation.

Purpose of the Study:

  • To quantify the number of additional prostate cancer diagnoses attributable to PSA testing.
  • To determine the number of prostate cancer deaths averted by PSA screening.
  • To estimate the ratio of additional diagnoses to averted deaths.

Main Methods:

  • Utilized regression models to analyze prostate cancer incidence and mortality data from 1983-1991 and 1992-2003.
  • Calculated expected incidence and mortality for 1992-2003 using pre-screening (1983-1991) and screening-era (1992-2003) data.
  • Compared estimated incidence and mortality to assess the effect of PSA screening introduction.

Main Results:

  • For men aged 50-69 between 1992-2003, opportunistic PSA screening prevented an estimated 512 prostate cancer deaths.
  • PSA testing identified 9,648 additional men with asymptomatic prostate cancer during the same period.
  • An estimated 18.8 asymptomatic prostate cancer cases were identified for every prostate cancer death prevented.

Conclusions:

  • PSA screening in Austria led to a substantial increase in prostate cancer diagnoses, with a significant number of deaths averted.
  • The ratio of identified asymptomatic cases to prevented deaths suggests potential overdiagnosis.
  • Further research is needed to determine the clinical significance of screen-detected prostate cancers that may not have otherwise become symptomatic.