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Updated: Jun 22, 2026

Analysis of LINE-1 Retrotransposition at the Single Nucleus Level
Published on: April 23, 2016
Chromodomains and LTR retrotransposons in plants
1Institute of Cytology and Genetics SB RAS; Novosibirsk, Russia.
Abstract:
A chromodomain is a domain contained in various proteins involved in chromatin remodeling and the regulation of gene expression in eukaryotes during development. Chromodomains perform a wide range of diverse functions including chromatin targeting and interactions between different proteins, RNA and DNA. The chromodomains also have been found as an additional domain at the C-terminal region of Polyproteins (Pol) encoded by transposable elements, which belong to the Gypsy LTR retrotransposons superfamily. Chromoviruses or chromodomain-containing Gypsy LTR retrotransposons form the most widespread clade of Gypsy LTR retrotransposons and can be found in diverse eukaryotes including plants, fungi and vertebrates. The recent finding suggested that chromodomains can be responsible for the targeted integration of LTR retrotransposons and, thus, should be favorable for mobile elements by allowing them to avoid negative selection arising from insertion into coding regions.
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