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Published on: October 17, 2018
Warfarin-induced intracerebral hemorrhage associated with microbleeds
Gha-Hyun Lee1, Sun U Kwon, Dong-Wha Kang
1Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Background:
Microbleeds (MBs), proposed as a biomarker for microangiopathy, have been suggested as a predictor of spontaneous or thrombolysis-related intracerebral hemorrhage (ICH) in acute ischemic stroke. However, the relationship between MBs and warfarin-induced ICH is not clear.
Case Report:
We describe two patients who developed warfarin-induced ICH at the site of MBs documented in previous MRI.
Conclusions:
The presence of MBs might increase the risk of ICH after warfarin use in ischemic stroke patients. A large cohort study is required to confirm the relationship of MBs with warfarin-induced ICH.
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