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Updated: Jun 22, 2026

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
Published on: May 28, 2014
Synthesis and spectroscopic properties of modular platinum(II) terpyridine phosphorescent pockets
Wah-Leung Tong1, Michael C W Chan, Nianyong Zhu
1Department of Biology and Chemistry and Centre for Marine Environmental Research and Innovative Technology, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong, China.
Abstract:
A modular design approach has been utilized to develop molecular 'pockets' featuring three integrated components, namely a phosphorescent Pt(II)-pi(organic) moiety, a suitable receptor group, and a rigid, conjugated connecting backbone, and the cavities therein are examined by NMR spectroscopy and an X-ray crystal structure. Their photophysical properties have been investigated; unusually for Pt-terpyridine derivatives, the complexes are luminescent (near-red (3)MLCT emission) in solution at room temperature. It has been shown that their emissive characteristics are affected by the nature of the backbone component but not the receptor group.
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