Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Covert hypothyroidism presenting as a cardiovascular event.

H J LeMar1, S G West, C R Garrett

  • 1Department of Medicine, Fitzsimons Army Medical Center, Aurora, Colorado 80045.

The American Journal of Medicine
|November 11, 1991
PubMed
Summary

Covert hypothyroidism can mimic cardiovascular disease, presenting with elevated creatine phosphokinase (CPK) levels. Early diagnosis through thyroid function tests and treatment with thyroid hormone therapy resolves symptoms and CPK elevations.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Stress responses to repeated exposure to a combined physical and social evaluative laboratory stressor in young healthy males.

Psychoneuroendocrinology·2015
Same author

Association between KRAS mutation and lung metastasis in advanced colorectal cancer.

British journal of cancer·2014
Same author

Effects of a DASH-like diet containing lean beef on vascular health.

Journal of human hypertension·2014
Same author

Acute effects of pistachio consumption on glucose and insulin, satiety hormones and endothelial function in the metabolic syndrome.

European journal of clinical nutrition·2014
Same author

Personalism and cognitive labels as determinants of attitude attribution.

Memory & cognition·2013
Same author

Nutrient displacement associated with walnut supplementation in men.

Journal of human nutrition and dietetics : the official journal of the British Dietetic Association·2013

Area of Science:

  • Endocrinology
  • Cardiology

Background:

  • Hypothyroidism often presents with classic symptoms, but can also manifest subtly.
  • Subtle hypothyroidism may present with cardiovascular symptoms and elevated creatine phosphokinase (CPK).

Observation:

  • This study details six patients where hypothyroidism was suspected due to persistently elevated CPK levels.
  • These patients exhibited symptoms suggestive of cardiovascular disease without clear myocardial damage.

Findings:

  • Thyroid function tests confirmed hypothyroidism in all six patients.
  • Thyroid hormone replacement therapy led to the resolution of both clinical symptoms and elevated CPK levels.

Implications:

  • Persistently elevated CPK in patients with cardiovascular symptoms warrants consideration of underlying hypothyroidism.

Related Experiment Videos

  • Recognizing covert hypothyroidism is crucial for accurate diagnosis and effective treatment, preventing unnecessary cardiac investigations.