[Clinico-morphological parallels among stomach cancer patients]

The paper reports the demographic and clinical data on more than 1,100 stomach cancer patients who underwent radical surgery in 1970-2007. Significant changes in structure and histological pattern of that pathology and primarily the growing fraction of signet ring and undifferentiated cell cancer (30%) are evident. It was matched by similarly important changes in the demographic and clinical data on patients with different morphological patterns and extent of tumor cell differentiation. Precise correlations between morphological pattern and loco-regional extent, site, size, pattern of growth and polyneoplasia rate were identified. Such characteristics should be taken into account when devising diagnostic and therapeutic strategies.