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Updated: Jun 22, 2026

Tension-Free Weight-Bearing Model of Steroid-Induced Osteonecrosis of Femoral Head in Rats
Published on: September 27, 2024
[Glucocorticoid-induced osteoporosis treatment algorithm]
J Payer1, Z Killinger, K Brázdilová
1V. interná klinika Lekárskej fakulty UKa FNsP Bratislava, Slovenská republika. payer@ruzinov.fnspba.sk
Abstract:
An excess amount of glucocorticoids represents the primary and most frequent etiological factor influencing secondary osteoporosis. The patients receiving glucocorticoids, but also those with the endogenous form of hypercorticism are at high risk for the loss of bone density, with the subsequent occurrence of pathological fractures. In this review, we summarize the currently available methods of prevention and the treatment of glucocorticoid-induced osteoporosis (GIO). We also include a proposal for both prophylactic and therapeutic approach that takes into account the risk factors typical for long-term users of glucocorticoids.
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