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Osteopathic Manipulative Treatment as a Useful Adjunctive Tool for Pneumonia
Published on: May 6, 2014
Treatment of nursing home-acquired pneumonia
Kyle Mills1, A Christie Graham, Bradford T Winslow
1Swedish Medical Center, Englewood, CO 80113, USA. kmills1@uwyo.edu
Abstract:
Pneumonia is an important cause of morbidity and mortality in nursing home residents, with 30-day mortality rates ranging from 10 to 30 percent. Streptococcus pneumoniae is the most common cause of nursing home-acquired pneumonia, although Staphylococcus aureus and gram-negative organisms may be more common in severe cases. Antibiotic therapy for nursing home-acquired pneumonia should target a broad range of organisms, and drug-resistant microbes should be considered when making treatment decisions. In the nursing home setting, treatment should consist of an antipneumococcal fluoroquinolone alone or either a high-dose beta-lactam/beta-lactamase inhibitor or a second- or third-generation cephalosporin, in combination with azithromycin. Treatment of hospitalized patients with nursing home-acquired pneumonia requires broad-spectrum antibiotics with coverage of many gram-negative and gram-positive organisms, including methicillin-resistant S. aureus. Appropriate dosing of antibiotics for nursing home-acquired pneumonia is important to optimize effectiveness and avoid adverse effects. Because many nursing home residents take multiple medications, it is important to consider possible drug interactions.
Insights
Pneumonia in nursing homes causes significant illness and death. Treatment requires broad-spectrum antibiotics targeting various bacteria, including drug-resistant strains, with careful dosing and consideration of drug interactions.
Area of Science:
- Infectious Diseases
- Geriatric Medicine
- Pharmacology
Background:
- Pneumonia is a leading cause of morbidity and mortality in nursing home residents.
- Thirty-day mortality rates for nursing home-acquired pneumonia range from 10% to 30%.
Purpose of the Study:
- To outline appropriate antibiotic therapy for nursing home-acquired pneumonia.
- To emphasize the importance of targeting a broad range of organisms, including drug-resistant microbes.
- To highlight considerations for antibiotic dosing and drug interactions in this population.
Main Methods:
- Review of common pathogens causing nursing home-acquired pneumonia.
- Analysis of recommended antibiotic regimens for nursing home residents.
- Consideration of treatment for hospitalized patients with nursing home-acquired pneumonia.
Main Results:
- Streptococcus pneumoniae is the most common cause, but Staphylococcus aureus and gram-negative organisms are frequent in severe cases.
- Recommended treatments include antipneumococcal fluoroquinolones or beta-lactam/beta-lactamase inhibitors/cephalosporins with azithromycin for nursing home residents.
- Hospitalized patients require broad-spectrum antibiotics covering gram-positive and gram-negative organisms, including MRSA.
Conclusions:
- Antibiotic selection for nursing home-acquired pneumonia must consider common and resistant pathogens.
- Appropriate dosing and awareness of drug interactions are crucial for effective and safe treatment.
- Effective management of nursing home-acquired pneumonia is vital to reduce morbidity and mortality.
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