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Updated: Jun 22, 2026
07:36
Clinical Application of Intense Pulsed Light Therapy and Radio Frequency for Treatment of Ocular Surface Diseases
Published on: July 3, 2025
[Ocular dryness related to systemic medications]
1Service d'Ophtalmologie, hôpital général, CHU de Dijon, 3, rue du Faubourg Raines, BP 159, 21033 Dijon cedex, France. catherine.creuzot-garcher@chu-dijon.fr
Journal Francais D'Ophtalmologie
|June 12, 2009
Summary
Iatrogenic ocular dry eye disease, often caused by medications, affects tear production. Treatment focuses on lubricants and reducing dehydrating systemic drugs.
Area of Science:
- Ophthalmology
- Endocrinology
- Pharmacology
Context:
- Iatrogenic ocular dry eye disease is a common complication.
- Hormonal and nervous systems regulate lacrimal secretion.
- Anticholinergic drugs can cause hyposecretion, leading to dry eye.
Purpose:
- To review the causes and management of iatrogenic ocular dry eye.
- To highlight the role of hormonal factors, particularly androgens, in ocular dryness.
- To discuss rare but severe causes like graft-versus-host disease and Lyell disease.
Summary:
- Medication-induced dry eye is frequent, linked to factors affecting tear secretion.
- Androgens significantly impact lacrimal and meibomian gland function, relevant in menopause and hormone therapy.
- Prompt identification of rare causes like GVHD and Lyell disease is crucial.
Impact:
- Informs clinicians about diverse causes of iatrogenic dry eye.
- Emphasizes the importance of considering hormonal influences and systemic medications.
- Guides treatment strategies prioritizing lubricants and minimizing dehydrating therapies.
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