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Updated: Jun 22, 2026

Anatomically Inspired Three-dimensional Micro-tissue Engineered Neural Networks for Nervous System Reconstruction, Modulation, and Modeling
Published on: May 31, 2017
CNS regeneration: only on one condition
1Department of Neurosciences, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA. jxs10@po.cwru.edu
Abstract:
The mammalian CNS is usually not capable of regeneration. However, conditioning dorsal root ganglion neurons by first lesioning their peripheral axons allows for regeneration of their central axons later on within the spinal cord. New work shows that, even if the sequence of lesioning is reversed, regeneration through the CNS lesion can rapidly occur under certain conditions.
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