Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 22, 2026

Pupillometry to Assess Auditory Sensation in Guinea Pigs
09:25

Pupillometry to Assess Auditory Sensation in Guinea Pigs

Published on: January 6, 2023

Detecting phasic lapses in alertness using pupillometric measures.

Sean D Kristjansson1, John A Stern, Timothy B Brown

  • 1Department of Psychiatry, Washington University School of Medicine, St. Louis, MO 63108, USA. kristjas@psychiatry.wustl.edu

Applied Ergonomics
|June 12, 2009
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ultra-low-level measurements of airborne fission products from the Fukushima Daiichi reactor accident using high volume collection systems at Savannah River National Laboratory.

Journal of environmental radioactivity·2022
Same author

Extending the Human Connectome Project across ages: Imaging protocols for the Lifespan Development and Aging projects.

NeuroImage·2018
Same author

Effects of Parkinson disease and antiparkinson medication on central adaptations to repetitive grasping.

Life sciences·2018
Same author

Cardiorespiratory interactions: Noncontact assessment using laser Doppler vibrometry.

Psychophysiology·2016
Same author

Neural correlates of inhibitory control and functional genetic variation in the dopamine D4 receptor gene.

Neuropsychologia·2014
Same author

Novel Applications of Laser Doppler Vibration Measurements to Medical Imaging.

Sensing and imaging·2014

Pupil size changes can indicate cognitive activity. This study found that specific pupillary response parameters can detect lapses in alertness during vigilance tasks, suggesting their use in monitoring operator states.

Area of Science:

  • Cognitive Neuroscience
  • Psychophysiology
  • Human Factors Engineering

Background:

  • Pupillary changes are reliable physiological indicators of cognitive processes.
  • Vigilance tasks are crucial for assessing sustained attention and operator alertness.
  • Detecting momentary lapses in alertness is vital for safety-critical operations.

Purpose of the Study:

  • To investigate the utility of pupillary changes in detecting transient decreases in alertness during a vigilance task.
  • To develop and validate quantitative parameters from single task-evoked pupillary responses (TEPRs).
  • To establish neurocognitive markers for real-time monitoring of operator alertness.

Main Methods:

  • A polynomial curve-fitting method was employed to analyze single TEPRs.

More Related Videos

Assessing Pupil-linked Changes in Locus Coeruleus-mediated Arousal Elicited by Trigeminal Stimulation
07:26

Assessing Pupil-linked Changes in Locus Coeruleus-mediated Arousal Elicited by Trigeminal Stimulation

Published on: November 26, 2019

The Rodent Psychomotor Vigilance Test (rPVT): A Method for Assessing Neurobehavioral Performance in Rats and Mice
07:47

The Rodent Psychomotor Vigilance Test (rPVT): A Method for Assessing Neurobehavioral Performance in Rats and Mice

Published on: December 29, 2016

Related Experiment Videos

Last Updated: Jun 22, 2026

Pupillometry to Assess Auditory Sensation in Guinea Pigs
09:25

Pupillometry to Assess Auditory Sensation in Guinea Pigs

Published on: January 6, 2023

Assessing Pupil-linked Changes in Locus Coeruleus-mediated Arousal Elicited by Trigeminal Stimulation
07:26

Assessing Pupil-linked Changes in Locus Coeruleus-mediated Arousal Elicited by Trigeminal Stimulation

Published on: November 26, 2019

The Rodent Psychomotor Vigilance Test (rPVT): A Method for Assessing Neurobehavioral Performance in Rats and Mice
07:47

The Rodent Psychomotor Vigilance Test (rPVT): A Method for Assessing Neurobehavioral Performance in Rats and Mice

Published on: December 29, 2016

  • Comparison of TEPR parameters (pupil diameter, dilation rates) between alert and low-alertness states.
  • Multilevel modeling framework used to analyze differences in response parameters.

    • Main Results:

    • Three specific TEPR parameters significantly differed between high and low alertness states: pupil diameter, linear pupil dilation rate, and curvilinear pupil dilation rate.
    • Longer latency responses, indicative of reduced alertness, were associated with distinct pupillary dynamics.
    • The findings demonstrate quantifiable differences in pupillary behavior correlating with alertness levels.

    Conclusions:

    • Pupillary response parameters show promise as objective neurocognitive markers for operator alertness.
    • These findings support the development of bio-behavioral systems for monitoring operator state.
    • Further research can refine these markers for practical applications in vigilance and monitoring systems.