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Multicolor Fluorescence Detection for Droplet Microfluidics Using Optical Fibers
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Published on: May 5, 2016

Optical detection in microfluidic systems.

Klaus B Mogensen1, Jörg P Kutter

  • 1Department of Micro and Nanotechnology, Technical University of Denmark (DTU), Kgs. Lyngby, Denmark.

Electrophoresis
|June 12, 2009
PubMed
Summary

Recent advances in microfluidic optical detection focus on integrated, low-cost polymer solutions. This review highlights optofluidics and planar waveguides to boost commercialization of these analytical devices.

Area of Science:

  • Optics and Photonics
  • Microfluidics
  • Analytical Chemistry

Background:

  • Optical detection is crucial for microfluidic systems.
  • Recent advancements focus on integrated optical solutions.
  • Commercialization of microfluidic devices has been limited.

Purpose of the Study:

  • To critically review recent progress in optical detection for microfluidics.
  • To emphasize integrated solutions like planar waveguides and optofluidics.
  • To discuss the analytical performance and cost-effectiveness of various detection schemes.

Main Methods:

  • Review of scientific literature published within the last two years.
  • Focus on integrated optical detection techniques.
  • Analysis of coupling schemes, evanescent-wave detectors, and optofluidics.

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Fluorescence detection methods for microfluidic droplet platforms
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Main Results:

  • Significant progress in integrated optical detection schemes.
  • Increased focus on low-cost polymer materials for mass production.
  • Development of novel coupling methods and evanescent-wave detectors.

Conclusions:

  • Integrated optics offer promising avenues for microfluidic measurements.
  • Cost-effective polymer-based solutions are key for commercialization.
  • Further development is needed to increase the impact on commercial devices.