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Cardiomyopathy I: Introduction and Classification01:25

Cardiomyopathy I: Introduction and Classification

Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...
Cardiomyopathy IV: Restrictive Cardiomyopathy01:29

Cardiomyopathy IV: Restrictive Cardiomyopathy

Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
Disturbances in Heart Rhythm01:29

Disturbances in Heart Rhythm

Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias01:25

ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias

Arrhythmia is a condition characterized by an irregular heart rhythm, with ECG changes that differ based on its origin and nature. The types of arrhythmias discussed below include atrial, junctional, and ventricular arrhythmias.Atrial ArrhythmiasPremature Atrial Complexes (PACs): PACs are early atrial beats caused by stress, caffeine, alcohol, electrolyte imbalances, hypoxia, hyperthyroidism, or certain medications (e.g., bronchodilators and decongestants). The ECG shows early P waves with an...
Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...

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European Society of Cardiology updated curriculum for heart failure nurses: developed by the Heart Failure Association, in collaboration with the Association of Cardiovascular Nurses and Allied Professions of the European Society of Cardiology.

European journal of heart failure·2026
Same author

Author Correction to "Canadian Cardiovascular Society/Canadian Heart Failure Society 2025 Guideline Update for Pharmacologic Management of Heart Failure With Nonreduced Ejection Fraction (LVEF > 40%) [Canadian Journal of Cardiology, Volume 41, Issue 10, Pages 1857-1874. DOI: 10.1016/j.cjca.2025.07.027]".

The Canadian journal of cardiology·2026
Same author

Author Correction for Canadian Cardiovascular Society/Canadian Heart Failure Society 2025 Guideline Update for Pharmacologic Management of Heart Failure With Nonreduced Ejection Fraction (LVEF > 40%): [Canadian Journal of Cardiology. Volume 41, Issue 10, October 2025, Pages 1857-1874. doi:10.1016/j.cjca.2025.07.027].

The Canadian journal of cardiology·2026
Same author

WITHDRAWN: Corrigendum to Canadian Cardiovascular Society/Canadian Heart Failure Society 2025 Guideline Update for Pharmacologic Management of Heart Failure With Nonreduced Ejection Fraction (LVEF > 40%).: Volume 41, Issue 10, October 2025, Pages 1857-74.

The Canadian journal of cardiology·2025
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Canadian Cardiovascular Society/Canadian Heart Failure Society 2025 Guideline Update for Pharmacologic Management of Heart Failure With Nonreduced Ejection Fraction (LVEF > 40%).

The Canadian journal of cardiology·2025
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Arterial Stiffness Is Associated With QTc Interval Prolongation in Patients With Heart Failure.

Biological research for nursing·2017
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Related Experiment Video

Updated: Jun 22, 2026

Rat Model of Right-Sided Cardiac Remodeling and Arrhythmia Using Pulmonary Artery Banding
10:39

Rat Model of Right-Sided Cardiac Remodeling and Arrhythmia Using Pulmonary Artery Banding

Published on: August 30, 2024

Arrhythmogenic right ventricular cardiomyopathy.

Rodolfo Pike1

  • 1Cardiac/Critical Care Program, Health Science Centre, St. John's, NL. Rodolfo.pike@easternhealth.ca

Canadian Journal of Cardiovascular Nursing = Journal Canadien En Soins Infirmiers Cardio-Vasculaires
|June 13, 2009
PubMed
Summary

Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a heart condition where heart muscle is replaced by scar tissue, potentially causing sudden death in young adults. Diagnosis and treatment, including defibrillators and medication, are crucial for managing this inherited cardiac disorder.

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Generation and Characterization of Right Ventricular Myocardial Infarction Induced by Permanent Ligation of the Right Coronary Artery in Mice
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Last Updated: Jun 22, 2026

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Dual-Dye Optical Mapping of Hearts from RyR2R2474S Knock-In Mice of Catecholaminergic Polymorphic Ventricular Tachycardia
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Generation and Characterization of Right Ventricular Myocardial Infarction Induced by Permanent Ligation of the Right Coronary Artery in Mice
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Generation and Characterization of Right Ventricular Myocardial Infarction Induced by Permanent Ligation of the Right Coronary Artery in Mice

Published on: February 1, 2022

Area of Science:

  • Cardiology
  • Genetics
  • Pathology

Background:

  • Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a significant cause of sudden cardiac death in young adults.
  • The condition involves the replacement of ventricular myocardium with fibro-fatty tissue.
  • Familial links are present in 30-50% of ARVC cases, highlighting its hereditary nature.

Purpose of the Study:

  • To summarize the key aspects of arrhythmogenic right ventricular cardiomyopathy.
  • To outline the diagnostic challenges and therapeutic strategies for ARVC.
  • To underscore the importance of understanding ARVC's genetic basis and clinical impact.

Main Methods:

  • Review of existing literature on arrhythmogenic right ventricular cardiomyopathy.
  • Analysis of diagnostic criteria and clinical manifestations.
  • Summary of current treatment modalities for ARVC.

Main Results:

  • ARVC is characterized by fibro-fatty replacement of the right ventricular myocardium.
  • Sudden cardiac death is a primary concern, particularly in young individuals.
  • Genetic predisposition plays a role in a substantial proportion of cases.

Conclusions:

  • Early diagnosis and management are vital for patients with ARVC.
  • Treatment often involves implantable defibrillators and pharmacotherapy to manage arrhythmias.
  • Understanding the familial implications of ARVC is essential for affected families.