Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Potentiometry: Membrane Electrodes01:15

Potentiometry: Membrane Electrodes

Membrane electrodes, also known as p-ion electrodes, use membranes that selectively interact with free analyte ions, generating a potential difference across the membrane. The resulting membrane potential, known as the asymmetry potential, is not zero even when analyte concentrations on both sides of the membrane are equal. The membrane's response is typically not selective to a single analyte but proportional to the concentration of all ions in the sample solution capable of interacting at the...
Resting Membrane Potential01:24

Resting Membrane Potential

The relative difference in electrical charge, or voltage, between the inside and the outside of a cell membrane, is called the membrane potential. It is generated by differences in permeability of the membrane to various ions and the concentrations of these ions across the membrane.
The Inside of a Neuron is More Negative
The membrane potential of a cell can be measured by inserting a microelectrode into a cell and comparing the charge to a reference electrode in the extracellular fluid. The...
Resting Membrane Potential01:24

Resting Membrane Potential

The relative difference in electrical charge, or voltage, between the inside and the outside of a cell membrane, is called the membrane potential. It is generated by differences in permeability of the membrane to various ions and the concentrations of these ions across the membrane.
The Inside of a Neuron is More Negative
The membrane potential of a cell can be measured by inserting a microelectrode into a cell and comparing the charge to a reference electrode in the extracellular fluid. The...
The Resting Membrane Potential01:21

The Resting Membrane Potential

Overview
Junction Potentials in Galvanic Cells01:21

Junction Potentials in Galvanic Cells

The Nernst equation, derived under the assumption of thermodynamic equilibrium, calculates the electromotive force (emf) as the sum of potential differences at phase boundaries in a reversible cell without a liquid junction. However, in irreversible cells such as the Daniell cell, an additional potential difference named the liquid-junction potential (EJ) arises across the interface of two electrolyte solutions due to different ion diffusion rates. This EJ represents the potential difference...
Resting Potential Decay01:15

Resting Potential Decay

The resting membrane potential of a neuron (-70mV) is sustained due to the selective ion permeability of the membrane. At the resting potential, the membrane is slightly permeable to ions like sodium (Na+) and chloride (Cl−) and highly permeable to potassium ions (K+). Differences in the ions' concentration inside the cell compared to the outside are maintained by membrane transport proteins like channels and pumps.
At rest, the K+ is the main ion that moves across the membrane through...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effect of chemical structure on the subglass relaxation dynamics of biobased polyesters as revealed by dielectric spectroscopy: 2,5-furandicarboxylic acid vs. trans-1,4-cyclohexanedicarboxylic acid.

Physical chemistry chemical physics : PCCP·2018
Same author

Tunable dielectric constant of water at the nanoscale.

Physical review. E, Statistical, nonlinear, and soft matter physics·2015
Same author

Asymmetric bi-layer PFSA membranes as model systems for the study of water management in the PEMFC.

Physical chemistry chemical physics : PCCP·2014
Same author

Zhu et al. reply.

Physical review letters·2013
Same author

Anomalous dielectric behavior of nanoconfined electrolytic solutions.

Physical review letters·2012
Same author

Laser-induced periodic surface structures nanofabricated on poly(trimethylene terephthalate) spin-coated films.

Langmuir : the ACS journal of surfaces and colloids·2012
Same journal

Conformational Positioning of the LXCXE Motif of LTSV40 within an Ordered-Disordered Transition Drives pRb Binding Cleft Recognition.

The journal of physical chemistry. B·2026
Same journal

Predicting Nirmatrelvir Resistance in SARS-CoV-2 M<sup>pro</sup> Mutants with an Integrated Computational Framework.

The journal of physical chemistry. B·2026
Same journal

From Cation Solvation to Anion Coordination: Lewis-Acidic Boranes Enable Halide Salt Electrolytes.

The journal of physical chemistry. B·2026
Same journal

In Vitro-Prepared A30P Alpha-Synuclein Fibrils Adopt the Conserved and Disease-Relevant Greek Key Fold.

The journal of physical chemistry. B·2026
Same journal

Metastructure Analysis of Self-Assembled Nanocubes with Different Equatorial Methyl Groups Based on Molecular Dynamics Simulations.

The journal of physical chemistry. B·2026
Same journal

A Cocoordinated <sup>1</sup>H Internal Reference Quantifies Proton-Exchange Bias in Coordinated-Water Diffusion.

The journal of physical chemistry. B·2026
See all related articles

Related Experiment Video

Updated: Jun 22, 2026

Realistic Membrane Modeling Using Complex Lipid Mixtures in Simulation Studies
07:31

Realistic Membrane Modeling Using Complex Lipid Mixtures in Simulation Studies

Published on: September 1, 2023

Membrane potential in multi-ionic mixtures.

Y Lanteri1, A Szymczyk, P Fievet

  • 1Institut UTINAM, UMR CNRS 6213, Universite de Franche-Comte, 16 route de Gray, Besancon Cedex 25030, France.

The Journal of Physical Chemistry. B
|June 13, 2009
PubMed
Summary
This summary is machine-generated.

This study theoretically investigates membrane potential using the SEDE model. Results show membrane potential depends on pore size and dielectric properties, offering a new characterization method.

More Related Videos

Merging Ion Concentration Polarization between Juxtaposed Ion Exchange Membranes to Block the Propagation of the Polarization Zone
08:06

Merging Ion Concentration Polarization between Juxtaposed Ion Exchange Membranes to Block the Propagation of the Polarization Zone

Published on: February 23, 2017

Related Experiment Videos

Last Updated: Jun 22, 2026

Realistic Membrane Modeling Using Complex Lipid Mixtures in Simulation Studies
07:31

Realistic Membrane Modeling Using Complex Lipid Mixtures in Simulation Studies

Published on: September 1, 2023

Merging Ion Concentration Polarization between Juxtaposed Ion Exchange Membranes to Block the Propagation of the Polarization Zone
08:06

Merging Ion Concentration Polarization between Juxtaposed Ion Exchange Membranes to Block the Propagation of the Polarization Zone

Published on: February 23, 2017

Area of Science:

  • Physical Chemistry
  • Materials Science
  • Electrochemistry

Background:

  • Membrane potential is crucial in various electrochemical applications.
  • Understanding ion transport through charged porous membranes is essential.
  • Existing models often simplify steric and dielectric effects.

Purpose of the Study:

  • To theoretically investigate membrane potential in charged porous membranes using the Steric, Electric, and Dielectric Exclusion (SEDE) model.
  • To analyze the influence of electrolyte mixture composition, pore size, and dielectric properties on membrane potential.
  • To propose a novel method for membrane characterization based on membrane potential measurements.

Main Methods:

  • Theoretical investigation using the Steric, Electric, and Dielectric Exclusion (SEDE) model.
  • Application of the Nernst-Planck formalism for transport phenomena.
  • Incorporation of modified Donnan equations, including steric and dielectric effects, for ion partitioning.
  • Analysis of both single salt solutions and multi-ionic systems.

Main Results:

  • The high concentration limit of membrane potential is dependent on mixture composition and pore size.
  • In multi-ionic systems, high concentration membrane potential depends on the effective dielectric constant within pores.
  • The low concentration limit is independent of mixture composition, pore size, and dielectric constant, but governed by counterion charge.
  • Membrane potential measurements can determine pore size and effective dielectric constant.

Conclusions:

  • The SEDE model provides a comprehensive framework for understanding membrane potential.
  • Membrane potential measurements offer a valuable, non-invasive method for characterizing charged porous membranes.
  • This approach eliminates the need for additional rejection rate measurements, simplifying membrane analysis.