Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

DNA as a Genetic Template02:05

DNA as a Genetic Template

Two structural features of the DNA molecule provide a basis for the mechanisms of heredity: the four nucleotide bases and its double-stranded nature. The Watson-Crick model of double-helical DNA structure, proposed in 1952, drew heavily upon the X-ray crystallography work of researchers Rosalind Franklin and Maurice Wilkins. Watson, Crick, and Wilkins jointly received the Nobel Prize in Physiology or Medicine for their work in 1962. Franklin was, controversially, excluded from the prize for...
The Small x Assumption02:20

The Small x Assumption

If a reaction has a small equilibrium constant, the equilibrium position favors the reactants. In such reactions, a negligible change in concentration may occur if the initial concentrations of reactants are high and the Kc value is small. In such circumstances, the equilibrium concentration is approximately equal to its initial concentration. This estimation can be used to simplify the equilibrium calculations by assuming that some equilibrium concentrations are equal to the initial...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Collaborative effects in polymer translocation and the appearance of fictitious free-energy barriers.

Physical review. E, Statistical, nonlinear, and soft matter physics·2014
Same author

Single polymer gating of channels under a solvent gradient.

Physical review. E, Statistical, nonlinear, and soft matter physics·2013
Same author

Translocation of short and long polymers through an interacting pore.

The Journal of chemical physics·2013
Same author

Generalized interacting self-avoiding trails on the square lattice: phase diagram and critical behavior.

Physical review. E, Statistical, nonlinear, and soft matter physics·2011
Same author

Hyperinsulinism with hypoglycemia relieved by removal of pancreatic tumor.

The American journal of digestive diseases·2010
Same author

Bethe approximation for the hydrogen-bonding self-avoiding walk in a solvent.

Physical review. E, Statistical, nonlinear, and soft matter physics·2008
Same journal

Tension on dsDNA bound to ssDNA-RecA filaments may play an important role in driving efficient and accurate homology recognition and strand exchange.

Physical review. E, Statistical, nonlinear, and soft matter physics·2016
Same journal

Publisher's Note: Amplitude-phase coupling drives chimera states in globally coupled laser networks [Phys. Rev. E 91, 040901(R) (2015)].

Physical review. E, Statistical, nonlinear, and soft matter physics·2016
Same journal

Erratum: Shapes of sedimenting soft elastic capsules in a viscous fluid [Phys. Rev. E 92, 033003 (2015)].

Physical review. E, Statistical, nonlinear, and soft matter physics·2016
Same journal

Erratum: Attenuation of excitation decay rate due to collective effect [Phys. Rev. E 90, 022142 (2014)].

Physical review. E, Statistical, nonlinear, and soft matter physics·2016
Same journal

Publisher's Note: Role of connectivity and fluctuations in the nucleation of calcium waves in cardiac cells [Phys. Rev. E 92, 052715 (2015)].

Physical review. E, Statistical, nonlinear, and soft matter physics·2016
Same journal

Publisher's Note: Lattice Boltzmann approach for complex nonequilibrium flows [Phys. Rev. E 92, 043308 (2015)].

Physical review. E, Statistical, nonlinear, and soft matter physics·2016
See all related articles

Related Experiment Video

Updated: Jun 22, 2026

Structure-Based Simulation and Sampling of Transcription Factor Protein Movements along DNA from Atomic-Scale Stepping to Coarse-Grained Diffusion
09:17

Structure-Based Simulation and Sampling of Transcription Factor Protein Movements along DNA from Atomic-Scale Stepping to Coarse-Grained Diffusion

Published on: March 1, 2022

Bethe approximation for a DNA-like self-avoiding walk model with variable solvent quality.

D P Foster1, C Pinettes

  • 1Laboratoire de Physique Théorique et Modélisation, CNRS UMR 8089, Université de Cergy-Pontoise, 2 ave A. Chauvin 95302 Cergy-Pontoise Cedex, France.

Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics
|June 13, 2009
PubMed
Summary
This summary is machine-generated.

This study models DNA zipping and unzipping transitions using the Bethe approximation. Solvent quality influences DNA thermodynamics, revealing diverse behaviors in this simple model.

More Related Videos

A Simple, Robust, and High Throughput Single Molecule Flow Stretching Assay Implementation for Studying Transport of Molecules Along DNA
12:05

A Simple, Robust, and High Throughput Single Molecule Flow Stretching Assay Implementation for Studying Transport of Molecules Along DNA

Published on: October 1, 2017

Unraveling Entropic Rate Acceleration Induced by Solvent Dynamics in Membrane Enzymes
09:42

Unraveling Entropic Rate Acceleration Induced by Solvent Dynamics in Membrane Enzymes

Published on: January 16, 2016

Related Experiment Videos

Last Updated: Jun 22, 2026

Structure-Based Simulation and Sampling of Transcription Factor Protein Movements along DNA from Atomic-Scale Stepping to Coarse-Grained Diffusion
09:17

Structure-Based Simulation and Sampling of Transcription Factor Protein Movements along DNA from Atomic-Scale Stepping to Coarse-Grained Diffusion

Published on: March 1, 2022

A Simple, Robust, and High Throughput Single Molecule Flow Stretching Assay Implementation for Studying Transport of Molecules Along DNA
12:05

A Simple, Robust, and High Throughput Single Molecule Flow Stretching Assay Implementation for Studying Transport of Molecules Along DNA

Published on: October 1, 2017

Unraveling Entropic Rate Acceleration Induced by Solvent Dynamics in Membrane Enzymes
09:42

Unraveling Entropic Rate Acceleration Induced by Solvent Dynamics in Membrane Enzymes

Published on: January 16, 2016

Area of Science:

  • Thermodynamics
  • Biophysics
  • Statistical Mechanics

Background:

  • DNA zipping and unzipping are fundamental processes in molecular biology.
  • Understanding DNA phase transitions is crucial for various biological functions.
  • Simple models are valuable for elucidating complex molecular behaviors.

Purpose of the Study:

  • To investigate the phase diagram and critical behavior of a toy DNA model.
  • To explore the influence of solvent quality on DNA thermodynamic properties.
  • To analyze the critical phenomena associated with DNA conformational changes.

Main Methods:

  • Utilizing the Bethe approximation for theoretical analysis.
  • Developing a simple toy model for DNA zipping/unzipping.
  • Incorporating solvent quality as a key parameter.

Main Results:

  • The study successfully mapped the phase diagram of the DNA model.
  • Critical behavior was analyzed within the Bethe approximation framework.
  • Varying solvent quality led to diverse thermodynamic outcomes.

Conclusions:

  • The Bethe approximation provides insights into DNA zipping/unzipping thermodynamics.
  • Solvent quality significantly impacts DNA phase transitions.
  • The toy model demonstrates a range of thermodynamic behaviors influenced by the environment.