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Related Concept Videos

Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure01:16

Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure

Oxygen therapy has emerged as a significant tool in enhancing the quality of life for patients suffering from pulmonary arterial hypertension (PAH). While this therapy has principally been studied on patients with significant hypoxemia, this therapeutic approach helps prevent potential organ damage and can be administered in the comfort of one's home.
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue, improving...
Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen01:16

Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen

Oxygen therapy is a pivotal aspect of medical care, particularly for patients with respiratory ailments. Two prominent oxygen-delivering systems include the Venturi mask and the transtracheal oxygen catheter.
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...
Physiological Control of Respiration01:23

Physiological Control of Respiration

Introduction
Breathing, a seemingly passive process, is regulated by the respiratory center in the brainstem. This center coordinates the involuntary control of respirations, which means it occurs without conscious effort, ensuring a smooth and uninterrupted pattern.
Regulation of Ventilation
The body maintains ventilation by monitoring levels of carbon dioxide (CO2), oxygen (O2), and hydrogen ion concentration (pH) in the arterial blood. Among these factors, the level of CO2 plays a crucial...
Chronic Obstructive Pulmonary Disease-V: Management01:29

Chronic Obstructive Pulmonary Disease-V: Management

Managing Chronic Obstructive Pulmonary Disease (COPD) involves a multifaceted approach to reduce symptoms, prevent exacerbations, improve overall health status, and slow disease progression. Key strategies include lifestyle modifications, pharmacotherapy, supportive therapies, and, in some cases, surgery. Here is an overview of the primary COPD management strategies:
Smoking Cessation
Oxygen Transport in the Blood01:27

Oxygen Transport in the Blood

Hemoglobin (Hb) is a crucial molecule in the human body, consisting of four polypeptide chains, each bound to an iron-containing heme group. This unique structure enables hemoglobin to bind to oxygen, with each molecule capable of combining with four molecules of oxygen, leading to rapid and reversible oxygen loading. When fully loaded with oxygen, it is called oxyhemoglobin, while hemoglobin that has released oxygen is called reduced hemoglobin or deoxyhemoglobin. As hemoglobin binds oxygen,...
COPD: Management Using Bronchodilators and Corticosteroids01:26

COPD: Management Using Bronchodilators and Corticosteroids

Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...

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May oxygen-ozone therapy improves cardiovascular disorders?

Velio Bocci1, Valter Travagli, Iacopo Zanardi

  • 1Department of Physiology, University of Siena, Via Aldo Moro 2, 53100 Siena, Italy. bocci@unisi.it

Cardiovascular & Hematological Disorders Drug Targets
|June 13, 2009
PubMed
Summary

Ozonated autohemotherapy may help manage age-related vascular disorders like chronic limb ischemia by addressing underlying inflammation and oxidative stress. This approach offers a novel strategy to complement existing treatments for these serious conditions.

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Area of Science:

  • Gerontology and Vascular Medicine
  • Regenerative Medicine and Oxidative Stress Research

Background:

  • Aging populations face significant health challenges from vascular disorders such as chronic limb ischemia, heart failure, cerebral ischemia, and age-related macular degeneration.
  • These conditions share common pathological features including ischemia, chronic inflammation, and tissue degeneration.
  • Current medical treatments, while effective for specific aspects, often fail to adequately reduce chronic oxidative stress, a key factor in disease progression.

Purpose of the Study:

  • To propose ozonated autohemotherapy as an adjunctive treatment for age-related vascular disorders.
  • To investigate its potential as a biological response modifier to counteract pathological progression.
  • To address the unmet need in managing chronic oxidative stress associated with these diseases.

Main Methods:

  • The study proposes the integration of ozonated autohemotherapy into existing treatment paradigms.
  • This therapeutic approach involves using the patient's own blood, treated with ozone, and reinfused.
  • The focus is on its role as a modifier of biological response.

Main Results:

  • Ozonated autohemotherapy is presented as a method to potentially block the pathological progress of vascular disorders.
  • It aims to address the persistent issue of chronic oxidative stress.
  • The therapy is suggested to modify the biological response to disease processes.

Conclusions:

  • Ozonated autohemotherapy offers a promising complementary strategy for managing complex vascular disorders in aging individuals.
  • By targeting oxidative stress and inflammation, it may help mitigate disease progression.
  • This approach represents a novel therapeutic avenue for serious age-related vascular conditions.