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Epidemiology, pathogenicity and emerging resistances in Staphylococcus pasteuri: from mammals and lampreys, to man
Vincenzo Savini1, Chiara Catavitello, Azaira Bianco
1Department of Transfusion Medicine, 'Spirito Santo' Hospital, Pescara, Italy. vincsavi@yahoo.it
Abstract:
Staphylococcus pasteuri is a coagulase-negative, Gram positive organism which is emerging as an agent of nosocomial infections and a blood derivatives contaminant, though its role in causing human disease mostly remains controversial. Despite the paucity of isolates recovered, this bacterium has recently appeared to express resistance against several classes of antibiotic compounds, such as methicillin/oxacillin, macrolides, lincosamides, streptogramins, tetracyclines, chloramphenicol, streptomycin, fosfomycin, as well as quaternary ammonium compounds. Also, authors will discuss some essential patents related to the topic reviewed.
Insights
Staphylococcus pasteuri, an emerging nosocomial pathogen, shows concerning antibiotic resistance. This review highlights its growing threat and discusses relevant patents.
Area of Science:
- Microbiology
- Infectious Diseases
- Antimicrobial Resistance
Background:
- Staphylococcus pasteuri is a coagulase-negative, Gram-positive bacterium.
- It is increasingly implicated in nosocomial infections and blood product contamination.
- Its role in human disease remains debated, but emerging resistance is a concern.
Purpose of the Study:
- To review the current understanding of Staphylococcus pasteuri.
- To highlight its emerging role as a pathogen.
- To discuss its documented antibiotic resistance patterns and related patents.
Main Methods:
- Literature review of Staphylococcus pasteuri.
- Analysis of reported cases and resistance data.
- Review of relevant patents.
Main Results:
- Staphylococcus pasteuri exhibits resistance to multiple antibiotic classes, including methicillin/oxacillin, macrolides, and tetracyclines.
- It also shows resistance to quaternary ammonium compounds.
- Several patents related to Staphylococcus pasteuri and its treatment exist.
Conclusions:
- Staphylococcus pasteuri is an emerging opportunistic pathogen with significant antimicrobial resistance.
- Its clinical significance warrants further investigation.
- Understanding resistance mechanisms and patent landscapes is crucial for future interventions.
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