Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Endocarditis I: Introduction01:25

Endocarditis I: Introduction

Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
Rocky Mountain Spotted Fever01:26

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The need for cardiac surgery differential tariffs in Israel at the era of aging population and emerging technology: Importance of procedure type and patient complexity as assessed by EuroSCORE.

Israel journal of health policy research·2021
Same author

Effects of commercial metronidazole and metronidazole benzoate suspensions on food intake in chinchillas.

The Journal of small animal practice·2020
Same author

Million-year lag times in a post-orogenic sediment conveyor.

Science advances·2020
Same author

Comparing abundance distributions and range maps in spatial conservation planning for migratory species.

Ecological applications : a publication of the Ecological Society of America·2019
Same author

PD-L1 receptor expression in vulvar carcinomas is HPV-independent.

Virchows Archiv : an international journal of pathology·2018
Same author

Reducing blood culture contamination using a departmental report card.

The Journal of hospital infection·2018
Same journal

Impact of low-dose chest CT and multiplex PCR on antibiotic usage for community-acquired pneumonia: multicentre prospective controlled before-after study with cluster randomisation (CAP-NEXT study).

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2026
Same journal

Clinical Microbiology and Infection: how did we do in 2025?

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2026
Same journal

Automate the work, not the decision: aligning expectations for AI in clinical microbiology.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2026
Same journal

Doxycycline prophylaxis and gonococcal resistance: reassurance, residual signals, and the case for surveillance.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2026
Same journal

Oral metronidazole versus clindamycin to treat bacterial vaginosis in pregnancies at risk for preterm labor.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2026
Same journal

Efficacy and safety of a radiographic severity-stratified all-oral short treatment regimen for multidrug/rifampicin-resistant tuberculosis in China: An open-label, multi-center,randomized controlled, non-inferiority trial.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2026
See all related articles

Related Experiment Videos

Q fever endocarditis; not always expected.

Y Wiener-Well1, D Fink, Y Schlesinger

  • 1Infectious Disease Unit, Shaare Zedek Medical Centre, affiliated with the Hadassah-Hebrew University Medical School, Jerusalem, Israel. yonitw@zahav.net.il

Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases
|June 13, 2009
PubMed
Summary
This summary is machine-generated.

Q fever endocarditis can be difficult to diagnose, sometimes requiring valve replacement surgery. Early detection through histopathological and serological evaluation is crucial for effective treatment of this chronic Coxiella burnetii infection.

Related Experiment Videos

Area of Science:

  • Infectious Diseases
  • Cardiology
  • Pathology

Background:

  • Q fever endocarditis is a chronic infection with varied clinical presentations.
  • Diagnosis can be challenging, often presenting atypically.
  • It can lead to severe complications like congestive heart failure.

Purpose of the Study:

  • To review the clinical and serological features of Q fever endocarditis.
  • To highlight diagnostic challenges, particularly in patients undergoing elective valve surgery.
  • To summarize treatment outcomes and antibody responses.

Main Methods:

  • Retrospective review of nine patients diagnosed with Q fever endocarditis over 19 years.
  • Analysis of clinical data, serological tests, and histopathological findings.
  • Evaluation of antibiotic treatment and antibody titers during follow-up.

Main Results:

  • Four patients (44%) required valve replacement due to heart failure.
  • Three patients were diagnosed post-surgery via valve pathology and serology, initially presenting without typical endocarditis signs.
  • All patients received antibiotic treatment with decreasing Q fever antibody titers over time.

Conclusions:

  • Histopathological examination of heart valves, even after elective replacement, is recommended.
  • Suspected Q fever endocarditis warrants comprehensive evaluation including anti-Coxiella burnetii antibody testing.
  • Early and accurate diagnosis is vital for managing this complex condition.