Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Documentation of Nursing Diagnosis01:10

Documentation of Nursing Diagnosis

The nurse documents nursing diagnoses and enters them into the patient record. The identified patient's nursing diagnosis is either written out with a plan of care or entered into the electronic health record.
In some settings, data-driven computerized decision support systems are in place, allowing for more accurate nursing diagnoses. The database within one of these systems includes diagnostic labels defining characteristics, activities, and indicators for nursing. A nurse enters assessment...
What is Cancer?02:12

What is Cancer?

Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...
What is Cancer?02:12

What is Cancer?

Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...
Cancers Originate from Somatic Mutations in a Single Cell02:21

Cancers Originate from Somatic Mutations in a Single Cell

Cancer arises from mutations in the critical genes that allow healthy cells to escape cell cycle regulation and acquire the ability to proliferate indefinitely. Though originating from a single mutation event in one of the originator cells, cancer progresses when the mutant cell lines continue to gain more and more mutations, and finally, become malignant. For example, chronic myelogenous leukemia (CML) develops initially as a non-lethal increase in white blood cells, which progressively...
Cancers Originate from Somatic Mutations in a Single Cell02:21

Cancers Originate from Somatic Mutations in a Single Cell

Cancer arises from mutations in the critical genes that allow healthy cells to escape cell cycle regulation and acquire the ability to proliferate indefinitely. Though originating from a single mutation event in one of the originator cells, cancer progresses when the mutant cell lines continue to gain more and more mutations, and finally, become malignant. For example, chronic myelogenous leukemia (CML) develops initially as a non-lethal increase in white blood cells, which progressively...
Adaptive Mechanisms in Cancer Cells02:53

Adaptive Mechanisms in Cancer Cells

Cancer cells accumulate genetic changes at an abnormally rapid rate due to the defects in the DNA repair mechanisms. From an evolutionary perspective, such genetic instability is advantageous for cancer development. Mutant cell lines accumulate a series of beneficial mutations that contribute to their progression into cancer.
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

<i>Wolbachia</i> uses ankyrin repeats to target specific fly proteins.

mBio·2026
Same author

'One of the hardest things in medicine is challenging an initial diagnosis': interim diagnoses and missed opportunities for diagnosing cancer in primary care, a qualitative study.

The British journal of general practice : the journal of the Royal College of General Practitioners·2026
Same author

Assessing ethnic inequalities in diagnostic intervals of breast cancer among patients presenting symptoms to general practitioners in England.

Scientific reports·2026
Same author

Sociodemographic variation in symptomatic faecal immunochemical testing return: a population-based analysis of 125 659 patients.

The British journal of general practice : the journal of the Royal College of General Practitioners·2025
Same author

<i>Wolbachia</i> uses ankyrin repeats to target specific fly proteins.

bioRxiv : the preprint server for biology·2025
Same author

Differential Elasticity Affects Lineage Segregation of Embryonic Stem Cells.

Physical review letters·2025
Same journal

Learning disability register enrolment in young people in England: Cohort Study, 2015-2023.

The British journal of general practice : the journal of the Royal College of General Practitioners·2026
Same journal

Disparities in the uptake of learning disability (intellectual disability) annual health checks.

The British journal of general practice : the journal of the Royal College of General Practitioners·2026
Same journal

Recording of Pharmacy First consultations in general practice records in England: an observational study of the service's first year using OpenSAFELY.

The British journal of general practice : the journal of the Royal College of General Practitioners·2026
Same journal

"I have no idea who does the bone thing" A qualitative exploration of older women and healthcare professionals' experiences to guide improvements in osteoporosis care.

The British journal of general practice : the journal of the Royal College of General Practitioners·2026
Same journal

Enriching New-onset Diabetes for Pancreatic Cancer (ENDPAC): External validation using English sentinel network.

The British journal of general practice : the journal of the Royal College of General Practitioners·2026
Same journal

Qualitative insights into identifying and managing polypharmacy: Patient, pharmacist and GP perspectives.

The British journal of general practice : the journal of the Royal College of General Practitioners·2026
See all related articles

Related Experiment Video

Updated: Jun 22, 2026

Isolation and Propagation of Circulating Tumor Cells from a Mouse Cancer Model
05:22

Isolation and Propagation of Circulating Tumor Cells from a Mouse Cancer Model

Published on: October 9, 2015

Five misconceptions in cancer diagnosis.

William Hamilton1

  • 1National School for Primary Care Research, Academic Unit of Primary Health Care, University of Bristol. w.hamilton@bristol.ac.uk

The British Journal of General Practice : the Journal of the Royal College of General Practitioners
|June 13, 2009
PubMed
Summary
This summary is machine-generated.

Investment in early cancer diagnosis facilities has not reduced mortality. Five misconceptions about cancer diagnosis hinder progress, impacting patient care and potentially causing delays for those with atypical symptoms.

Related Experiment Videos

Last Updated: Jun 22, 2026

Isolation and Propagation of Circulating Tumor Cells from a Mouse Cancer Model
05:22

Isolation and Propagation of Circulating Tumor Cells from a Mouse Cancer Model

Published on: October 9, 2015

Area of Science:

  • Oncology
  • Healthcare Management
  • Public Health

Background:

  • Significant investment has been made in early cancer diagnosis facilities.
  • The success of these investments in reducing cancer mortality remains unclear.
  • New rapid investigation facilities in the UK have not demonstrably reduced mortality rates.

Purpose of the Study:

  • To evaluate the effectiveness of early cancer diagnosis investments.
  • To identify reasons for the lack of mortality reduction despite facility improvements.
  • To address misconceptions hindering successful early cancer diagnosis.

Main Methods:

  • Analysis of investment in early cancer diagnosis facilities.
  • Review of data from new rapid investigation facilities in the UK.
  • Identification and description of five key misconceptions in cancer diagnosis.
  • Proposal of research and organizational remedies.

Main Results:

  • New facilities have not reduced cancer mortality and may delay diagnosis for some patients.
  • Five misconceptions impede the translation of investment into mortality benefits.
  • Misconceptions include the location of diagnosis, GP diagnostic skills, the role of symptomatic diagnosis versus screening, referral pressures, and nihilism about early diagnosis value.

Conclusions:

  • Early cancer diagnosis investments have not yet yielded expected mortality benefits.
  • Addressing misconceptions regarding cancer diagnosis pathways and value is crucial.
  • Reforming education, referral practices, and acknowledging the importance of symptomatic diagnosis are recommended.