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Published on: December 15, 2011
Celiac disease-related antibodies in Italian children with epilepsy
Lucio Giordano1, Monica Valotti, Adonella Bosetti
1Pediatric Neuropsychiatric Division, City Hospital of Brescia, Brescia, Italy.
Abstract:
Reports differ on the association between epilepsy and celiac disease, an immune-mediated enteropathy triggered by the ingestion of gluten in genetically susceptible individuals. In this study, 272 Italian children with epilepsy and 300 healthy children were screened for anti-gliadin and anti-transglutaminase immunoglobulin A and G; positive and borderline samples were tested for the presence of anti-endomysium antibodies. The prevalence of antibodies related to celiac disease was comparable to that of healthy controls. In keeping with this observation, Italian epileptic children should not be considered a group at risk for celiac disease.
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