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Updated: Jun 22, 2026

Procedures for In Vitro Cultivation of Treponema pallidum, the Syphilis Spirochete

Procedures for In Vitro Cultivation of Treponema pallidum, the Syphilis Spirochete

Published on: January 24, 2025

Syphilis, the great mimicker, is back.

Melanie Bissessor¹, Marcus Chen

¹Melbourne Sexual Health Centre, Victoria. mbissessor@mshc.org.au

Australian Family Physician

|June 13, 2009

Summary

Syphilis is re-emerging among men who have sex with men in Australia. Regular screening, prompt treatment, and partner management are crucial for controlling this sexually transmitted infection.

Area of Science:

Public Health
Infectious Diseases
Epidemiology

Background:

Syphilis (a sexually transmitted infection) has recently re-emerged in Australian urban centers.
This resurgence is particularly noted among men who have sex with men.

Purpose of the Study:

To review the clinical presentation and management of syphilis.
To outline strategies for enhancing syphilis control measures.

Main Methods:

Literature review of syphilis clinical features and management.
Analysis of syphilis control measures.

Main Results:

Syphilis presents with various clinical manifestations, including rashes and anogenital lesions.
Effective management requires adequate treatment and partner notification/treatment.

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Conclusions:

Syphilis should be suspected in men who have sex with men presenting with suggestive symptoms.
Regular serological screening for syphilis is recommended for men who have sex with men, including those with HIV.
Integrated management involving early detection, treatment, and partner services is key to controlling the current syphilis epidemic.