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Related Experiment Video

Updated: Jun 22, 2026

Development and Characterization of Fusidic Acid-Loaded Alginate-Aloe vera Based Hydrogel Film
04:09

Development and Characterization of Fusidic Acid-Loaded Alginate-Aloe vera Based Hydrogel Film

Published on: December 13, 2024

New bioactive compounds from Aloe hijazensis.

Howaida I Abd-Alla1, Mohamed Shaaban, Khaled A Shaaban

  • 1Department of Chemistry of Natural Compounds, Division of Pharmaceutical Industries, National Research Centre, Dokki-Cairo, Egypt.

Natural Product Research
|June 13, 2009
PubMed
Summary

This study identifies 22 chemical compounds from Aloe hijazensis, including new natural products. Extracts showed potent antibacterial and antifungal activities, highlighting the plant

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Last Updated: Jun 22, 2026

Development and Characterization of Fusidic Acid-Loaded Alginate-Aloe vera Based Hydrogel Film
04:09

Development and Characterization of Fusidic Acid-Loaded Alginate-Aloe vera Based Hydrogel Film

Published on: December 13, 2024

Area of Science:

  • Phytochemistry
  • Pharmacology
  • Natural Products Chemistry

Background:

  • Aloe species are known for their medicinal properties.
  • Limited research exists on the chemical constituents of Aloe hijazensis from Saudi Arabia.

Purpose of the Study:

  • To investigate the chemical constituents of Aloe hijazensis leaves and roots.
  • To evaluate the biological activities of the plant extracts.

Main Methods:

  • Phytochemical analysis using UV, NMR, and MS data.
  • Isolation and structure elucidation of 22 compounds.
  • Antimicrobial screening of plant extracts against various microbial strains.

Main Results:

  • Twenty-two compounds were isolated, including eight hydroxyquinones, a dihydro-isocoumarin, a triterpene, an anthrone, aloenin derivatives, and flavonoids.
  • Two compounds (6a and 10) are reported as new natural constituents.
  • Compounds 4, 5, 8, and 18 were reported for the first time from Aloe spp.
  • Plant extracts exhibited potent antibacterial and antifungal activities.

Conclusions:

  • Aloe hijazensis is a rich source of diverse chemical compounds, including novel natural products.
  • The plant possesses significant antimicrobial properties, warranting further investigation for therapeutic applications.