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Updated: Jun 22, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
Why haven't we generated sufficient evidence? Part I: Barriers to applied research
Abstract:
Factors accounting for the profession's dearth of effectiveness studies to date may include (1) confusion about the differences between basic and applied research, (2) biases in the academic system that promote and reward basic research activities, (3) greater public and private funding for basic research than for clinical (applied) research, (4) difficulties inherent in conducting effectiveness studies, and (5) competing responsibilities for faculty and clinician time commitments. Although these factors may impede occupational therapy researchers from participating in effectiveness studies, strategies can be developed to promote the profession's increased participation in evidence-based research. Part II of this editorial, which follows in the next AJOT issue, will examine possible solutions to overcome impediments and increase the profession's participation in research providing support for occupational therapy intervention.
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