Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Transcriptional activities of two newly identified Haemaphysalis longicornis tick-derived promoter regions in the Ixodes scapularis tick cell line (ISE6).

Insect molecular biology·2018
Same author

[Significance of preoperative ultrasound evaluation of the forearm arteries prior to coronary artery bypass grafting].

Kyobu geka. The Japanese journal of thoracic surgery·2010
Same author

[Mitral valve replacement in a patient with Sheehan's syndrome].

Kyobu geka. The Japanese journal of thoracic surgery·2008
Same author

[Modified infarction exclusion technique for surgical treatment of postinfarction ventricular septal rupture].

Kyobu geka. The Japanese journal of thoracic surgery·2008
Same author

Efficacy of a p38 mitogen activated protein kinase inhibitor in mitigating an established inflammatory reaction to polyethylene particles in vivo.

Journal of biomedical materials research. Part A·2008
Same author

[Repair of postoperative residual shunt of postinfarction ventricular septal perforation: report of a case].

Kyobu geka. The Japanese journal of thoracic surgery·2007
Same journal

[Secondary Pneumothorax due to Rupture of Pulmonary Rheumatoid Nodule:Report of a Case].

Kyobu geka. The Japanese journal of thoracic surgery·2026
Same journal

[Thoracoscopic Right Upper Lobectomy for Lung Cancer with Tracheal Bronchus:Report of a Case].

Kyobu geka. The Japanese journal of thoracic surgery·2026
Same journal

[Neoplastic Cardiac Tamponade Manifesting as Left Ventricular Diastolic Dysfunction:Report of a Case].

Kyobu geka. The Japanese journal of thoracic surgery·2026
Same journal

[Non-anastomotic Pseudoaneurysm due to Sternal Wire Removal After Ascending Aorta Grafting:Report of a Case].

Kyobu geka. The Japanese journal of thoracic surgery·2026
Same journal

[Successful Staged Total Aortic Replacement in a Young Patient with Marfan Syndrome:Report of a Case].

Kyobu geka. The Japanese journal of thoracic surgery·2026
Same journal

[Massive Left Ventricular Thrombus Following Steroid Therapy for Immunoglobulin( Ig) G4-related Ophthalmic Disease:Report of a Case].

Kyobu geka. The Japanese journal of thoracic surgery·2026
See all related articles

Related Experiment Video

Updated: Jun 22, 2026

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
12:17

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

[Aortic root reconstruction with Edwards Prima PLUS stentless valve].

M Sato1, E Suenaga, S Senaha

  • 1Department of Cardiovascular Surgery, Kouseikai Hospital, Nagasaki, Japan.

Kyobu Geka. the Japanese Journal of Thoracic Surgery
|June 16, 2009
PubMed
Summary
This summary is machine-generated.

Three male patients with severe aortic valve regurgitation underwent successful aortic root aneurysm repair using the Edwards Prima PLUS stentless valve. This innovative valve offers a promising treatment option for selected patients requiring aortic root reconstruction.

More Related Videos

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
14:14

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Published on: December 11, 2017

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement
08:50

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement

Published on: March 26, 2018

Related Experiment Videos

Last Updated: Jun 22, 2026

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
12:17

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
14:14

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Published on: December 11, 2017

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement
08:50

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement

Published on: March 26, 2018

Area of Science:

  • Cardiovascular Surgery
  • Medical Devices
  • Aortic Diseases

Background:

  • Aortic root aneurysms pose significant risks, often necessitating complex surgical interventions.
  • The Edwards Prima PLUS stentless valve, recently approved in Japan, presents a novel option for aortic valve and root repair.

Observation:

  • Three male patients (ages 69, 77, 69) with severe (Sellers' IV) aortic valve regurgitation and aortic root dilation underwent surgical repair.
  • Echocardiographic measurements revealed significant aortic annulus, Valsalva sinus, and sino-tubular junction diameters.

Findings:

  • All patients received aortic root reconstruction with the Edwards Prima PLUS stentless valve, with additional procedures in two cases (ascending aorta replacement, coronary artery bypass, pulmonary vein isolation, mitral annuloplasty).
  • Surgical durations ranged from 218 to 275 minutes.
  • All patients experienced uneventful postoperative courses, demonstrating successful treatment outcomes.

Implications:

  • The Edwards Prima PLUS stentless valve appears to be a suitable and effective option for aortic root aneurysm repair in carefully selected patients.
  • This case series highlights the successful application of a new stentless valve in complex cardiovascular procedures.
  • Further research and long-term follow-up are warranted to fully establish the valve's efficacy and durability.