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Updated: Jun 22, 2026

A Protocol for Computer-Based Protein Structure and Function Prediction
16:41

A Protocol for Computer-Based Protein Structure and Function Prediction

Published on: November 3, 2011

PSI-2: structural genomics to cover protein domain family space

Benoît H Dessailly1, Rajesh Nair, Lukasz Jaroszewski

  • 1Department of Structural and Molecular Biology, University College of London, London WC1E6BT, UK. benoit@biochem.ucl.ac.uk

Structure (London, England : 1993)
|June 16, 2009
PubMed

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Protein families are groups of homologous proteins; that is, they have similarities in amino acid sequences and three-dimensional structures. Protein families usually occur because of gene duplication, where an additional copy of a gene is inserted into the genome of an organism.   Mutations that change the amino acids but still allow the protein to be properly synthesized, will lead to new protein family members.   If these new proteins contain similar amino acids in key locations, protein...
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Structural proteins are a category of proteins responsible for functions ranging from cell shape and movement to providing support to major structures such as bones, cartilage, hair, and muscles. This group includes proteins such as collagen, actin, myosin, and keratin.
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