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Culture of Murine Embryonic Metatarsals: A Physiological Model of Endochondral Ossification
Published on: December 3, 2016
The growing skeleton: MR imaging appearances of developing cartilage
Paritosh C Khanna1, Mahesh M Thapa
1Department of Radiology, Seattle Children's Hospital, University of Washington School of Medicine, 4800 Sand Point Way NE, M/S-5417, Seattle, WA 98105, USA. pkhanna@u.washington.edu
Magnetic Resonance Imaging Clinics of North America
|June 16, 2009
Summary
This study details hyaline cartilage imaging in children, emphasizing tailored Magnetic Resonance (MR) imaging protocols. It covers normal cartilage features, optimization techniques, and common abnormalities for improved pediatric musculoskeletal assessments.
Area of Science:
- Pediatric Radiology
- Musculoskeletal Imaging
- Biochemistry
Background:
- Developing hyaline cartilage in long bones comprises epiphyseal, physeal, and articular components.
- Each cartilage component exhibits distinct imaging characteristics linked to its biochemical and macromolecular makeup.
- Standard adult MR imaging protocols are insufficient for pediatric cartilage evaluation.
Purpose of the Study:
- To present the biochemical and histologic features of normal pediatric hyaline cartilage.
- To describe MR imaging characteristics of normal pediatric hyaline cartilage.
- To provide a practical approach for optimizing MR imaging protocols for pediatric cartilage.
Main Methods:
- Review of biochemical and histologic features of hyaline cartilage.
- Description of MR imaging characteristics.
- Guidance on tailoring MR imaging protocols to pediatric developmental stages.
- Discussion of common abnormalities and advanced imaging techniques.
Main Results:
- Hyaline cartilage components have specific imaging signatures related to composition.
- Pediatric MR imaging requires developmental stage-specific protocol optimization.
- Abnormalities and advanced techniques are crucial for comprehensive assessment.
Conclusions:
- Optimized, tailored MR imaging protocols are essential for accurate pediatric hyaline cartilage assessment.
- Understanding biochemical and histologic features aids in interpreting MR imaging findings.
- This approach enhances the diagnosis of pediatric cartilage abnormalities.
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