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Transanal rectosigmoid resection for severe intractable idiopathic constipation
Marc A Levitt1, Colin A Martin, Richard A Falcone
1Division of Pediatric General and Thoracic Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA. marc.levitt@cchmc.org
Insights
Transanal rectosigmoid resection effectively treats severe idiopathic constipation in children refractory to medical management. This surgical approach significantly reduces laxative dependence and improves continence, offering a viable alternative to other surgical interventions.
Area of Science:
- Pediatric Surgery
- Gastroenterology
- Colorectal Surgery
Background:
- Idiopathic constipation significantly impacts children's quality of life.
- A portion of pediatric patients with constipation do not respond to medical treatments.
- Surgical intervention is necessary for refractory cases of idiopathic constipation.
Purpose of the Study:
- To introduce and evaluate a novel transanal surgical technique for managing medically intractable idiopathic constipation in children.
- To assess the efficacy of transanal rectosigmoid resection in reducing symptoms and medication reliance.
Main Methods:
- Retrospective review of 288 patients with severe idiopathic constipation and soiling.
- Surgical intervention involved transanal full-thickness rectosigmoid resection with colo-anal anastomosis for patients refractory to medical management and with megarectosigmoid.
- Analysis of preoperative and postoperative laxative use and continence status.
Main Results:
- Fifteen patients underwent transanal rectosigmoid resection, with an average of 43 cm of rectosigmoid resected.
- Postoperative laxative requirements decreased significantly from 68 mg senna/day to 8.6 mg/day (P < .001).
- Nine patients achieved complete continence, one experienced manageable diarrhea, and two had occasional soiling due to noncompliance.
Conclusions:
- Transanal rectosigmoid resection is an effective surgical option for children with intractable idiopathic constipation.
- The procedure leads to substantial reduction or elimination of laxative use while maintaining or improving continence.
- This technique presents a valuable alternative to more invasive surgeries like colonic resections or stomas.
Introduction:
Idiopathic constipation is a source of significant morbidity in children. A subset of patients is refractory to medical therapy and requires surgical intervention. We present a novel surgical technique for the management of these patients.
Methods:
We reviewed the records of 288 patients with severe idiopathic constipation and soiling. Patients who were refractory to medical management and had a megarectosigmoid underwent a transanal full-thickness rectosigmoid resection with a primary colo-anal anastomosis.
Results:
Fifteen patients underwent a transanal rectosigmoid resection. The preoperative contrast enema demonstrated an enormously dilated rectosigmoid in 14. An average of 43 cm (range, 8-98 cm) of rectosigmoid was resected. Of 14 patients with more than 3 months of follow-up, the preoperative laxative dose was 68 mg of senna/d (range, 52-95 mg), which decreased to 8.6 mg postoperatively (P < .001). Nine patients are clean without soiling, 1 is more prone to diarrhea, but is clean. Two patients soil occasionally, but are noncompliant, and 2 were lost to follow-up.
Conclusion:
Transanal rectosigmoid resection for medically intractable idiopathic constipation resulted in a dramatic reduction or elimination in laxatives use while preserving continence. It is a useful alternative to surgical options such as other colonic resections, antegrade enemas, and stomas.
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